Reliability and Validity of the Massachusetts General Hospital Cognitive and Physical Functioning Questionnaire
Reliability and Validity of the Massachusetts General Hospital Cognitive and Physical Functioning Questionnaire
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DOI：
10.1159/000201934
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发表时间：
2009-01-01
影响因子：
22.8
通讯作者：
Baer, Lee
中科院分区：
文献类型：
--
作者：
Fava, Maurizio;Iosifescu, Dan V.;Baer, Lee
背景：我们最近开发了马萨诸塞州总医院认知和身体功能问卷（CPFQ），这是一个衡量情绪和焦虑症认知和执行功能障碍的简短量表，我们在此报告其可靠性和有效性。方法：通过根据抑郁症门诊患者样本中 CPFQ 7 个项目的平均相互相关性计算克朗巴赫系数 α，并通过对同一样本的数据进行因子分析来评估 CPFQ 的内部一致性，以确认该量表是单因子的并测量单一结构。通过计算治疗前筛查分数和治疗前基线分数之间的皮尔逊相关系数，在不同的抑郁症门诊患者样本中评估了 CPFQ 的重测可靠性。通过计算第二个抑郁症门诊患者样本中积极治疗条件下受试者的相关 t 检验来评估 CPFQ 变化的敏感性。最后，以两种不同的方式评估 CPFQ 的收敛有效性。结果：我们发现CPFQ是一个单因子量表，具有很强的内部一致性。高重测可靠性表明它具有良好的时间稳定性。研究还发现，CPFQ 对治疗的变化很敏感，并且通过与其他嗜睡、疲劳、冷漠和神经心理功能指标的显着相关性显示出收敛效度。尽管正如预期的那样，CPFQ 与抑郁症的测量显着相关，但中等相关性（r 类似于 0.30）表明 CPFQ 测量的是不同的结构。结论：综上所述，CPFQ是一个单因子量表，具有较强的内部一致性、良好的时间稳定性和对治疗变化的敏感性。需要进一步的研究来评估该仪器在与认知功能障碍相关的其他精神和神经精神疾病中的有效性和可靠性。版权所有 (C) 2009 S. Karger AG，巴塞尔
Background: We have recently developed the Massachusetts General Hospital Cognitive and Physical Functioning Questionnaire (CPFQ), a brief scale to measure cognitive and executive dysfunction in mood and anxiety disorders, and we here report on its reliability and validity. Methods: The internal consistency of the CPFQ was assessed by computing Cronbach's coefficient alpha based upon the average intercorrelation of the 7 items of the CPFQ in a sample of depressed outpatients and by factor analyzing data from the same sample to confirm that the scale is unifactorial and measuring a single construct. Test-retest reliability of the CPFQ was assessed in a different sample of depressed outpatients by computing Pearson's correlation coefficient between pretreatment screening scores and pretreatment baseline scores. Sensitivity to change of the CPFQ was assessed by computing the dependent t test for the subjects in the active treatment condition in the second sample of depressed outpatients. Finally, convergent validity for the CPFQ was assessed in two different ways. Results: We found that the CPFQ is a unifactorial scale, with strong internal consistency. It has good temporal stability as indicated by high test-retest reliability. The CPFQ was also found to be sensitive to change with treatment and displayed convergent validity by significant correlations with other measures of sleepiness, fatigue, apathy and neuropsychological functioning. Although, as expected, the CPFQ was significantly correlated with a measure of depression, the moderate correlation (r similar to 0.30) indicates that the CPFQ is measuring a different construct. Conclusion: In summary, the CPFQ is a unifactorial scale, with strong internal consistency, good temporal stability and sensitivity to change with treatment. Further studies will be needed to assess the validity and reliability of this instrument in other psychiatric and neuropsychiatric conditions associated with cognitive dysfunction. Copyright (C) 2009 S. Karger AG, Basel