Prevalence of erectile dysfunction in patients with metabolic syndrome
Prevalence of erectile dysfunction in patients with metabolic syndrome
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DOI：
10.1111/j.1442-2042.2006.01310.x
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发表时间：
2006-04-01
影响因子：
2.6
通讯作者：
Demir, Tevfik
中科院分区：
文献类型：
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作者：
Demir, Tevfik
目的：目的：探讨代谢综合征与勃起功能障碍（艾德）的关系。所有患者都被要求填写国际勃起功能指数（IIEF）调查问卷。根据国家胆固醇教育计划（NCEP）成人治疗小组（ATP）-III，当存在五种风险因素中的任何三种或更多种时，确定存在代谢综合征。结果：代谢综合征组89例（33%），艾德状态与代谢综合征危险因素的关系采用Logistic回归分析。代谢综合征患者和非代谢综合征患者的IIEF-EF域评分分别为17.7 +/- 7.9和21.7 +/- 7.5（P < 0.001）。74%的代谢综合征患者和50%的非代谢综合征患者发生艾德（P < 0.001;比值比2.9; 95%CI 1.7-5.0）。勃起功能领域评分随代谢危险因素的增加而显著降低（P < 0.001）。具有空腹血糖（FBG）、腰围（WC）或高血压（HT）危险因素的患者勃起功能评分低于具有其他代谢危险因素的患者。结论：代谢综合征可能是艾德的潜在危险因素，建议对代谢综合征患者进行有关艾德的询问，WC的测定可作为评价ED的一个重要指标。
Aim: We wished to investigate the relationship between metabolic syndrome and erectile dysfunction (ED).Materials and methods: A total of 268 patients were included in this study. All of the patients were asked to fill in an International Index for Erectile Function (IIEF) questionnaire. The presence of metabolic syndrome was determined when any three or more of the five risk factors were present according to the National Cholesterol Education Program (NCEP) Adult Treatment Panel (ATP)-III. The relationship between risk factor for metabolic syndrome and ED status was determined according to logistic regression analysis.Results: Eighty-nine patients (33%) constituted the metabolic syndrome group. IIEF-EF domain scores of patients with and without metabolic syndrome were 17.7 +/- 7.9 and 21.7 +/- 7.5, respectively (P < 0.001). Seventy-four percent of patients with metabolic syndrome and 50% of patients without metabolic syndrome had ED (P < 0.001; odds ratio 2.9; 95% CI 1.7-5.0). Erectile function domain scores significantly decreased as the number of metabolic risk factors increased (P < 0.001). Patients with the risk factor of fasting blood glucose (FBG), waist circumference (WC), or hypertension (HT) had lower erectile function domain scores than the patients with other metabolic risk factors. Logistic regression analysis revealed that FBG and WC were the most important criteria for ED.Conclusions: Metabolic syndrome seems to be a potential risk factor for ED. We recommend patients with metabolic syndrome should be questioned about ED, and WC measurement might take part in the evaluation of ED.