Abnormal left ventricular diastolic filling patterns in small-for-gestational-age infants

Abnormal left ventricular diastolic filling patterns in small-for-gestational-age infants
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DOI:
10.1016/s0378-3782(97)00122-9
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发表时间:
1998-07-10
影响因子:
2.5
通讯作者:
Takada, G
Takada, G
中科院分区:
医学4区
文献类型:
--
作者:
Harada, K;Suzuki, T;Takada, G

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多普勒二尖瓣血流速度模式在评估小于胎龄儿左心室舒张功能方面的作用还不清楚。本研究的目的是检查小于胎龄儿(n = 13)的多普勒充盈模式,并将其与年龄匹配的适于胎龄儿(n = 29)进行比较。我们测量了早期心房收缩(A波)和心房收缩(E波峰值)的峰值流速、E波峰值与A波峰值的比值(E/A波峰值)、E波(VTIE波)和A波(VTIA波)的速度时间积分、VTIE波与VTIA波的比值(VTIE/A波)、第1/3充盈分数、标准化为每搏输出量的峰值充盈率和减速时间。平均胎龄和心率在合适胎龄婴儿和小于胎龄婴儿之间没有显着差异。小于胎龄儿的平均出生体重显著低于适于胎龄儿(802 ± 220 g vs. 1184 ± 260 g,P
Doppler transmitral flow velocity patterns in assessing left ventricular diastolic function in small-for-gestational-age infants have been poorly understood. The purpose of this study is to examine Doppler filling patterns in small-for-gestational-age infants (n = 13) and to compare them with those in age-matched appropriate-for-gestational-age infants (n = 29). We measured peak flow velocities of early diastole (peak E wave) and atrial contraction (peak A wave), ratio of peak E wave to peak A wave (peak E/A wave), velocity time integrals of E wave (VTIE wave) and A wave (VTIA wave), ratio of VTIE wave to VTIA wave (VTIE/A wave), first third filling fraction, peak filling rate normalized to stroke volume, and deceleration time. Mean gestational age and heart rate did not show a significant difference between the appropriate- and the small-for-gestational-age infants. The mean birth weight in the small-for-gestational-age infants was significantly lower than that in the appropriate-for-gestational-age infants (802+/-220 vs. 1184+/-260 g, P