Environmental Risk Factors for Community-Acquired Pneumonia Hospitalization in Older Adults
Environmental Risk Factors for Community-Acquired Pneumonia Hospitalization in Older Adults
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DOI：
10.1111/j.1532-5415.2009.02259.x
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发表时间：
2009-06-01
影响因子：
6.3
通讯作者：
Marrie, Thomas J.
中科院分区：
文献类型：
--
作者：
Loeb, Mark;Neupane, Binod;Marrie, Thomas J.
探讨老年人因肺炎住院治疗的风险与生物物理环境因素的关系。基于人群的病例对照研究，收集个人访谈数据。安大略的汉密尔顿和阿尔伯塔的埃德蒙顿，加拿大。717名65岁及以上的人因社区获得性肺炎（CAP）住院从2002年9月至2005年4月，867名年龄在65岁及以上的对照者随机选择来自同一社区的病例。肺炎风险与环境和其他变量的比值比（OR）。（OR=1.73，95%置信区间（CI）=1.04-2.90）;营养评分较差（OR=1.83，95%CI =1.19-2.80）;每月饮酒（每克; OR=1.69，95% CI=1.08-2.61）;工作中经常暴露于气体、烟雾或化学品的历史（OR=3.69，95%CI =2.37-5.75）;有在家中经常接触溶剂、油漆或汽油烟雾的病史多因素分析显示，在家中讲非英语（OR = 5.31，95%CI =2.60-10.87）与肺炎住院的风险相关。年龄、充血性心力衰竭、慢性阻塞性肺疾病、吞咽困难、肾脏疾病、功能状态、免疫抑制疾病药物的使用以及一生吸烟史超过100支是与肺炎住院相关的其他变量。
To investigate the risk of hospitalization for pneumonia in older adults in relation to biophysical environmental factors.Population-based case control study with collection of personal interview data.Hamilton, Ontario, and Edmonton, Alberta, Canada.Seven hundred seventeen people aged 65 and older hospitalized for community-acquired pneumonia (CAP) from September 2002 to April 2005 and 867 controls aged 65 and older randomly selected from the same communities as the cases.Odds ratios (ORs) for risk of pneumonia in relation to environmental and other variables.Exposure to secondhand smoke in the previous month (OR=1.73, 95% confidence interval (CI)=1.04-2.90); poor nutritional score (OR=1.83, 95% CI=1.19-2.80); alcohol use per month (per gram; OR=1.69, 95% CI=1.08-2.61); history of regular exposure to gases, fumes, or chemicals at work (OR=3.69, 95% CI=2.37-5.75); history of regular exposure to fumes from solvents, paints, or gasoline at home (OR=3.31, 95% CI=1.59-6.87); and non-English language spoken at home (OR=5.31, 95% CI=2.60-10.87) were associated with a greater risk of pneumonia hospitalization in multivariable analysis. Age, congestive heart failure, chronic obstructive lung disease, dysphagia, renal disease, functional status, use of immunosuppressive disease medications, and lifetime history of smoking of more than 100 cigarettes were other variables associated with hospitalization for pneumonia.In elderly people, present and past exposures in the physical environmental are associated with hospitalization for CAP.