Global stability of a delayed HIV infection model with nonlinear incidence rate
Global stability of a delayed HIV infection model with nonlinear incidence rate
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具有非线性发病率的延迟 HIV 感染模型的全局稳定性
DOI:
10.1007/s11071-011-0219-8
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发表时间:
2012-04
影响因子:
5.6
通讯作者:
Xianhua Tang
中科院分区:
文献类型:
--
作者:
Zhaohui Yuan;Zhongjun Ma;Xianhua Tang
Under the assumption that the incidence rate of the infection and the removal rate of the infective by cytotoxic T lymphocytes are nonlinear, we study the global dynamics of a HIV infection model with the response of the immune system using characteristic equation, the Fluctuation lemma, and the direct Lyapunov method. The existence of a threshold parameter, i.e., the basic reproduction number or basic reproductive ratio is established and the global stability of the equilibria is discussed.
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DOI:
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