ESOPHAGITIS AND GASTRODUODENAL DISORDERS ASSOCIATED WITH DIABETIC GASTROPARESIS
ESOPHAGITIS AND GASTRODUODENAL DISORDERS ASSOCIATED WITH DIABETIC GASTROPARESIS
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DOI：
10.1001/archinte.147.8.1477
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发表时间：
1987-08-01
影响因子：
--
通讯作者：
SCHWARTZ, SS
中科院分区：
文献类型：
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作者：
PARKMAN, HP;SCHWARTZ, SS
回顾性研究了4年期间入住费城宾夕法尼亚大学医院[宾夕法尼亚州，美国]的糖尿病胃轻瘫患者的所有数据，以了解糖尿病胃轻瘫相关胃肠道疾病的患病率。20例顽固性恶心和呕吐的糖尿病患者，被认为是继发于糖尿病胃轻瘫，在几天内对胃轻瘫的常规治疗无效后接受了上消化道内镜检查。9例（45%）患者的上消化道内镜检查结果正常。11名（55%）患者被发现患有其他胃肠道疾病，可以解释他们持续的恶心和呕吐症状。具体而言，3例患者有念珠菌性食管炎，4例糜烂性食管炎，2例胃溃疡，1例十二指肠糜烂，1例胆汁反流性胃炎。这11名患者在改变治疗方法以治疗他们的其他疾病时有所改善。糖尿病胃轻瘫的管理进行了讨论，重点是早期上消化道内镜检查的病人谁没有回应最初的治疗。
The prevalence of associated gastrointestinal disorders with diabetic gastroparesis was studied retrospectively by reviewing all data on patients with diabetic gastroparesis who were admitted to the Hospital of the University of Pennsylvania, Philadelphia [Pennsylvania, USA], over a four-year period. Twenty diabetic patients with intractable nausea and vomiting, thought to be secondary to diabetic gastroparesis, underwent upper gastrointestinal tract endoscopy after failure to respond to conventional therapy for gastroparesis within several days. Nine (45%) patients had normal upper endoscopic examination results. Eleven (55%) patients were discovered to have other gastrointestinal tract disorders that could explain their persistent symptoms of nausea and vomiting. Specifically, three patients had Candida esophagitis, four had erosive esophagitis, two had gastric ulcers, one had duodenal erosions, and one had bile reflux gastritis. These 11 patients improved when therapy was altered to treat their additional disorder. Managemment of diabetic gastroparesis is discussed with emphasis on early upper gastrointestinal tract endoscopy for patients who fail to respond to therapy initially.