Clinical characteristics of perineal endometriosis: A case series.
Clinical characteristics of perineal endometriosis: A case series.
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会阴子宫内膜异位症的临床特征：病例系列。
DOI：
10.12998/wjcc.v9.i5.1037
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发表时间：
2021-02-16
影响因子：
1.1
通讯作者：
Zhang J
中科院分区：
文献类型：
--
作者：
Liang Y;Zhang D;Jiang L;Liu Y;Zhang J
在接受手术治疗的子宫内膜异位症(EM)患者中，会阴子宫内膜异位症(PEM)的发病率很低。表现为会及周围有疼痛的硬结节或囊性结节。植入学说被认为是PEM的主要发病机制。关于PEM的发生率和临床特点的临床研究较少。本研究旨在总结14例PEM患者的临床资料，分析可能与潜伏期和疼痛有关的因素。分析PEM的病史、临床表现、诊断、治疗及治疗效果。本研究是一个案例系列。收集2009年1月至2019年12月在上海交通大学附属国际和平妇幼保健院就诊的14例PEM患者的临床资料和随访资料。统计分析采用配对t检验和皮尔逊相关分析。P<；0.05被认为具有统计学意义。纳入的14名患者均有阴道分娩史。所有患者均行PEM病变切除。3例行提肛肌修补术，1例行PEM扩大切除加肛门括约肌修补术。分娩时体重指数(BMI)和产后1个月内BMI分别与潜伏期呈负相关(R2=0.53/0.86，P<0.05)。所有患者术后3个月皮损视觉模拟评分平均为0.57±1.28，明显低于术前(P<；0.05)。1例患者在术后6个月内复发，到目前为止，第二次手术后没有复发。分娩时及产后1mo内BMI越高，胎膜早破潜伏期越短。术前评估病变部位是非常重要的。手术切除病变是治疗PEM的最好方法，可显著缓解症状。因此，在诊断为PEM后，建议立即手术治疗。
The prevalence of perineal endometriosis (PEM) is low among women with endometriosis (EM) treated by surgery. It manifests as hard or cystic nodules with pain in the perineal wounds and surrounding areas. Implantation theory is regarded as the main pathogenesis of PEM. There are few clinical studies on the incidence and clinical characteristics of PEM. This study aims to summarize the clinical data of 14 PEM cases and analyze the factors that may be related to the incubation period and pain. To analyze the medical history, clinical manifestations, diagnosis, treatment and treatment effect of PEM. The present study is a case series. We collected the clinical data and follow-up data of 14 patients with PEM who visited The International Peace Maternal and Child Health Hospital Affiliated to Shanghai Jiaotong University from January 2009 to December 2019. Paired t test and Pearson correlation analysis were used for statistical analysis. P < 0.05 was considered statistically significant. The 14 patients included had a history of vaginal delivery. All patients underwent PEM lesion resection. Three patients were treated by levator ani muscle repair at the same time and 1 patient underwent extensive PEM lesion resection and anal sphincter repair. Body mass index (BMI) at delivery and BMI within 1 mo after delivery were negatively correlated with the latent period, respectively (R2 = 0.53/0.86, P < 0.05). The average visual analog scale score in lesions at the third month after surgery was 0.57 ± 1.28 for all patients, which was significantly lower than that prior to surgery (P < 0.05). One patient relapsed during the sixth month after surgery, and to date, no recurrence occurred after the second surgery. The higher the BMI during delivery and within 1 mo after delivery, the shorter the incubation period of PEM. It is very important to evaluate the location of lesions before surgery. Surgical resection of the lesion is the best treatment for PEM and results in significant alleviation of symptoms. Therefore, following the diagnosis of PEM, immediate surgery is recommended.
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影响因子：
2.6
作者：
Buda, Alessandro;Ferrari, Luisa;Milani, Rodolfo
通讯作者：
Milani, Rodolfo
影响因子：
1.6
作者：
Nasu, Kaei;Okamoto, Mamiko;Narahara, Hisashi
通讯作者：
Narahara, Hisashi
影响因子：
3.9
作者：
Bacher, H;Schweiger, W;Mischinger, HJ
通讯作者：
Mischinger, HJ
影响因子：
3.9
作者：
Dougherty, LS;Hull, T
通讯作者：
Hull, T
DOI：
10.1016/j.jsbmb.2015.12.025
发表时间：
2016-04-01
影响因子：
4.1
作者：
Piccinato, Carla A.;Neme, Rosa M.;Ferriani, Rui A.
通讯作者：
Ferriani, Rui A.