European 'NAFLD Preparedness Index' - Is Europe ready to meet the challenge of fatty liver disease?
European 'NAFLD Preparedness Index' - Is Europe ready to meet the challenge of fatty liver disease?
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DOI：
10.1016/j.jhepr.2021.100234
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发表时间：
2021-04
期刊：
影响因子：
--
通讯作者：
Anstee QM
中科院分区：
文献类型：
--
作者：
Lazarus JV;Palayew A;Carrieri P;Ekstedt M;Marchesini G;Novak K;Ratziu V;Romero-Gómez M;Tacke F;Zelber-Sagi S;Cortez-Pinto H;Anstee QM
非酒精性脂肪性肝病(NAFLD)与肥胖、代谢综合征和糖尿病密切相关，是一种高度流行的新兴疾病，可以通过以患者为中心的多学科方法进行最佳治疗。国家做好应对NAFLD的准备对于确保卫生系统能够提供有效的护理至关重要。我们提出了欧洲NAFLD准备指数。2019年6月，来自29个国家的专家组提取了数据，完成了关于NAFLD的41个项目的调查问卷。问题分为4类：政策/民间社会(9个问题)、准则(16个问题)、流行病学(4个问题)和护理管理(12个问题)。根据答复，国家对每项指标的准备情况被分为低、中、高三个级别。然后，我们应用多重对应分析，获得了每个国家的标准化准备分数，范围从0到100。这项分析估计了一个汇总因素，可以解释数据集中71.3%的变化。没有发现任何国家达到高度戒备状态。目前，英国得分最高(75.5分)，但处于中等水平的准备范围内，其次是西班牙(56.2分)和丹麦(43.4分)，而卢森堡和爱尔兰得分最低，为4.9分。只有西班牙在流行病学指标类别中得分很高，而英国是唯一在护理管理方面得分较高的国家。NAFLD准备指数表明，各国应对NAFLD的准备程度有很大差异。值得注意的是，即使是得分相对较高的国家也在关键领域表现出不足，这表明需要进行结构性改革，以优化NAFLD管理并确保采取有效的公共卫生方法。非酒精性脂肪性肝病(NAFLD)与肥胖、代谢综合征和糖尿病密切相关，是一种高度流行的疾病，可以通过以患者为中心的多学科方法进行最佳治疗。为了能够采取有效的公共卫生措施以预防疾病，同时确保卫生系统能够向受影响的人口提供有效的护理，国家准备应对非传染性非传染性疾病是至关重要的。这项研究将防备定义为拥有适当的政策和民间社会的参与、指南、流行病学和护理管理。研究发现，所有29个国家都缺乏对NAFLD的准备，不同国家和所研究的4类国家之间差异很大。NAFLD是一种与肥胖、代谢综合征和糖尿病相关的高度流行的疾病，NAFLD可以通过以患者为中心的多学科方法进行最佳治疗。国家防备对于采取有效的公共卫生措施以预防疾病至关重要。NAFLD的防备意味着有适当的政策和民间社会的参与、指南、流行病学和护理管理。研究发现，所有29个国家对NAFLD的准备都是不足的。
Non-alcoholic fatty liver disease (NAFLD), which is closely associated with obesity, metabolic syndrome, and diabetes, is a highly prevalent emerging condition that can be optimally managed through a multidisciplinary patient-centred approach. National preparedness to address NAFLD is essential to ensure that health systems can deliver effective care. We present a NAFLD Preparedness Index for Europe. In June 2019, data were extracted by expert groups from 29 countries to complete a 41-item questionnaire about NAFLD. Questions were classified into 4 categories: policies/civil society (9 questions), guidelines (16 questions), epidemiology (4 questions), and care management (12 questions). Based on the responses, national preparedness for each indicator was classified into low, middle, or high-levels. We then applied a multiple correspondence analysis to obtain a standardised preparedness score for each country ranging from 0 to 100. The analysis estimated a summary factor that explained 71.3% of the variation in the dataset. No countries were found to have yet attained a high-level of preparedness. Currently, the UK (75.5) scored best, although falling within the mid-level preparedness band, followed by Spain (56.2), and Denmark (43.4), whereas Luxembourg and Ireland were the lowest scoring countries with a score of 4.9. Only Spain scored highly in the epidemiology indicator category, whereas the UK was the only country that scored highly for care management. The NAFLD Preparedness Index indicates substantial variation between countries’ readiness to address NAFLD. Notably, even those countries that score relatively highly exhibit deficiencies in key domains, suggesting that structural changes are needed to optimise NAFLD management and ensure effective public health approaches are in place. Non-alcoholic fatty liver disease (NAFLD), which is closely associated with obesity, metabolic syndrome, and diabetes, is a highly prevalent condition that can be optimally managed through a multidisciplinary patient-centred approach. National preparedness to address NAFLD is essential to allow for effective public health measures aimed at preventing disease while also ensuring that health systems can deliver effective care to affected populations. This study defined preparedness as having adequate policies and civil society engagement, guidelines, epidemiology, and care management. NAFLD preparedness was found to be deficient in all 29 countries studied, with great variation among the countries and the 4 categories studied. NAFLD is a highly prevalent condition associated with obesity, metabolic syndrome, and diabetes NAFLD can be optimally managed through a multidisciplinary patient-centred approach. National preparedness is essential to allow for effective public health measures aimed at preventing disease. NAFLD preparedness means having adequate policies and civil society engagement, guidelines, epidemiology, and care management. NAFLD preparedness was found to be deficient in all 29 countries studied.
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影响因子：
29.4
作者：
Kanwal F;Kramer JR;Mapakshi S;Natarajan Y;Chayanupatkul M;Richardson PA;Li L;Desiderio R;Thrift AP;Asch SM;Chu J;El-Serag HB
通讯作者：
El-Serag HB
影响因子：
82.9
作者：
Friedman SL;Neuschwander-Tetri BA;Rinella M;Sanyal AJ
通讯作者：
Sanyal AJ
影响因子：
29.4
作者：
Angulo P;Kleiner DE;Dam-Larsen S;Adams LA;Bjornsson ES;Charatcharoenwitthaya P;Mills PR;Keach JC;Lafferty HD;Stahler A;Haflidadottir S;Bendtsen F
通讯作者：
Bendtsen F
影响因子：
8.2
作者：
通讯作者：
--
影响因子：
25.7
作者：
Lazarus, Jeffrey, V;Ekstedt, Mattias;Dufour, Jean-Francois
通讯作者：
Dufour, Jean-Francois