Biological Properties of Staphylococcal Enterotoxin-Like Toxin Type R
Biological Properties of Staphylococcal Enterotoxin-Like Toxin Type R
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DOI：
10.1128/iai.72.6.3664-3667.2004
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发表时间：
2004-06
影响因子：
3.1
通讯作者：
K. Omoe;K. Imanishi;D. Hu;H. Kato;H. Takahashi-Omoe;A. Nakane;T. Uchiyama;K. Shinagawa
中科院分区：
文献类型：
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作者：
K. Omoe;K. Imanishi;D. Hu;H. Kato;H. Takahashi-Omoe;A. Nakane;T. Uchiyama;K. Shinagawa
摘要我们研究了一种新的葡萄球菌肠毒素样毒素R型（SElR）的生物学特性。SEIR刺激T细胞需要主要组织相容性复合物II类分子。SEIR刺激携带受体Vβ 3、11、12、13.2和14的T细胞。这些结果表明，SEIR作为超抗原。
ABSTRACT We investigated the biological properties of a novel staphylococcal enterotoxin-like putative toxin, staphylococcal enterotoxin-like toxin type R (SElR). Major histocompatibility complex class II molecules were required for T-cell stimulation by SElR. SElR stimulated T cells bearing receptors Vβ 3, 11, 12, 13.2, and 14. These results suggested that SElR acts as a superantigen.