Association between social and family support and antenatal depression: a hospital-based study in Chengdu, China
Association between social and family support and antenatal depression: a hospital-based study in Chengdu, China
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DOI：
10.1186/s12884-019-2510-5
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发表时间：
2019-11-19
影响因子：
3.1
通讯作者：
Wang, Yuqiong
中科院分区：
文献类型：
--
作者：
Hu, Ying;Wang, Ying;Wang, Yuqiong
背景：产前抑郁（AD）被认为是主要的健康负担之一，对孕妇和新生儿的结局有不利影响。本研究旨在调查成都市孕妇产前抑郁（AD）的患病率，并从个人背景、相关社会因素、家庭因素和认知因素等方面探讨AD的潜在危险因素。方法：采用前瞻性巢式病例对照研究，纳入2015年3月至2016年5月在成都市3家三级医院和1家区域医院接受产前护理的二胎孕妇。在孕中期和孕晚期给参与者自行设计问卷，收集临床和人口学特征信息，并使用修改版的爱丁堡产后抑郁量表（EPDS）来测量AD。分析采用了逻辑回归。结果：共纳入996例孕妇。93名妇女仅在妊娠中期出现阿尔茨海默病症状，96名仅在妊娠晚期出现阿尔茨海默病症状，107名在妊娠中期和晚期都表现出持续的抑郁症。在单变量分析中，年龄和婚姻关系与阿尔茨海默病在妊娠中期和晚期的发生有关。此外，年龄增加、全职工作、高等教育程度和配偶性别偏好与持续抑郁症的减少有关。多因素分析显示，性别偏好和婚姻关系是持续抑郁的潜在危险因素。结论：年龄、婚姻关系、与公婆的关系、对本次妊娠的消极认知和丈夫的性别偏好是某些特定孕期AD发生的危险因素。丈夫的性别偏好和婚姻关系与持续性抑郁独立相关。这些发现表明，强有力的家庭支持有助于改善孕妇的心理健康。
Background: Antenatal depression (AD) is considered as one of the major health burdens and has adverse effects on the outcome of expectant mothers and newborns. The present study aims to investigate the prevalence of antenatal depression (AD), and to explore the potential risk factors of AD among pregnant women in Chengdu, including personal background, related social factors, family factors and cognitive factors.Methods: The prospective nested case-control study included pregnant women who were in their second pregnancy and attended prenatal care at three tertiary hospitals and one regional hospital in Chengdu, China, between March 2015 and May 2016. Self-designed questionnaires were given to participants in their second and third trimesters to collect information on clinical and demographic characteristics, and a modified edition of Edinburgh Postnatal Depression Scale (EPDS) were used to measure AD. The logistic regression was applicated in analyses.Results: A total of 996 pregnant women were included in analysis. Ninety-three women suffered from AD symptoms only in their second trimester, 96 only in their third trimester, and 107 displayed persistent depression in both trimesters. In the univariate analyses, age and marital relationships were linked with AD occurrence in both second and third trimester. In addition, increasing age, full-time job, higher education level, and no gender preference of spouse were associated with reduced persistent depression. Multivariate analysis showed that gender preference and marital relationship were the potential risk factors of persistent depression.Conclusions: Age, marital relationship relationships, with parents-in-law, the negative recognition of this pregnancy and husband's gender preference were found as risk factors of AD occurrence in some specific trimester. Gender preference of husbands and marital relationships were independently associated with persistent depression. These findings suggest that stronger family support can help improve mental health of pregnant women.