Differential diagnosis and treatment of primary, cutaneous, anaplastic large cell lymphoma: not always an easy task
Differential diagnosis and treatment of primary, cutaneous, anaplastic large cell lymphoma: not always an easy task
复制标题
DOI：
10.1007/s12185-009-0365-7
复制
发表时间：
2009-09-01
影响因子：
2.1
通讯作者：
Hatzitolios, Apostolos
中科院分区：
文献类型：
--
作者：
Diamantidis, Michael D.;Papadopoulos, Athanasios;Hatzitolios, Apostolos
原发性皮肤间变性大细胞淋巴瘤（PC-ALCL）是一种罕见的和独特的肿瘤出现在皮肤上的新生。我们报告了一例75岁男性患者，在其左股骨区域诊断为PC-ALCL。我们描述病变的形态沿着的鉴别诊断，治疗，临床过程和预后。我们进一步讨论了诊断为PC-ALCL时应考虑的治疗参数。我们的病例报告显示了PC-ALCL的分类、分期、鉴别诊断和治疗选择的复杂性。强调临床标准结合免疫组织化学诊断PC-ALCL的重要性至关重要。
Primary cutaneous anaplastic large cell lymphoma (PC-ALCL) is a rare and distinct neoplasm appearing de novo on the skin. We present a case of a 75-year-old man diagnosed with PC-ALCL in his left femoral region. We describe the morphology of lesions along with the differential diagnosis, treatment, clinical course and prognosis. We further discuss parameters concerning treatment that should be considered when a PC-ALCL is diagnosed. Our case report demonstrates the complexity in classification, staging, differential diagnosis and therapy selection of PC-ALCLs. It is crucial to emphasize the importance of clinical criteria in diagnosing a PC-ALCL in combination with immunohistochemistry.