Canine congenital diaphragmatic hernia.
Canine congenital diaphragmatic hernia.
复制标题
犬先天性膈疝。
DOI：
10.1111/j.1939-1676.1988.tb02804.x
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发表时间：
1988
影响因子：
2.6
通讯作者：
Noden,DM
中科院分区：
文献类型：
--
作者：
Valentine,BA;Cooper,BJ;Dietze,AE;Noden,DM
在三对父女交配的 27 只小狗中，有 5 只都患有先天性膈疝，影响两性。一只纯种金毛猎犬是共同的父亲。该缺陷发生在膈肌的左背外侧部分，表明在胚胎发育过程中左胸膜腹膜管未能闭合。这些发现以及之前关于新生幼犬中类似缺陷的报告与犬膈肌缺陷的常染色体隐性遗传一致。
Congenital diaphragmatic hernia, affecting both sexes, was present in five of 27 puppies from three father‐daughter matings. A purebred Golden Retriever was the common sire. The defect occurred in the left dorsolateral portion of the diaphragm, suggesting failure of closure of the left pleuroperitoneal canal during embryonic development. These findings, and a previous report of a similar defect in neonatal puppies, are consistent with autosomal recessive inheritance of canine diaphragmatic defects.