The effect of pregnancy and lactation on food intake, gastrointestinal anatomy and the absorptive capacity of the small intestine in the albino rat
The effect of pregnancy and lactation on food intake, gastrointestinal anatomy and the absorptive capacity of the small intestine in the albino rat
复制标题
妊娠和哺乳期对白化大鼠食物摄入、胃肠道解剖和小肠吸收能力的影响
DOI：
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发表时间：
1975
影响因子：
3.6
通讯作者：
V. Williams
中科院分区：
文献类型：
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作者：
A. Cripps;V. Williams
1.对未孕大鼠(对照组)、妊娠大鼠和哺乳期大鼠的摄食量、体重、肠道器官解剖和小肠对L-亮氨酸和D(+)-葡萄糖的吸收能力进行了测定。2.孕期摄食量增加约60%，哺乳期进一步增加250%。3.妊娠对胃肠道的大体解剖无明显影响。有证据表明，怀孕期间小肠绒毛高度和水分百分比增加，结肠长度增加。4.在哺乳期，消化道重量和大小逐渐增加。断奶后部分消退。5.在断奶后20天内，除小肠长度外，所有解剖测量指标均完全回归到对照水平。断奶后第30天，肠道长度的增加尚未完全消退。6.妊娠期对葡萄糖和亮氨酸的绝对吸收无明显变化。7.哺乳过程中亮氨酸和葡萄糖的绝对吸收率增加。哺乳第10天吸收最大。8.单位长度吸收亮氨酸和葡萄糖的结果表明，在哺乳期和哺乳期后，粘膜细胞的吸收能力或吸收细胞数/mm发生了变化。
1. Food consumption, live weight, anatomical measurements on the gut organs and the absorptive capacity of the small intestine for L-leucine and D(+)-glucose were made on virgin (control), pregnant and lactating albino rats. 2. Food intake increased by approximately 60% during pregnancy and a further 250% during lactation. 3. Pregnancy did not markedly influence the gross anatomy of the gastrointestinal tract. There was evidence for increased villus height and percentage water in the small intestine and for increased length of the colon during pregnancy. 4. During lactation, the alimentary canal progressively increased in weight and size. It partially regressed following weaning. 5. All anatomical measurements, except the length of the small intestine, completely regressed to control values within 20 d of weaning. The increased intestinal length had not completely regressed by day 30 post-weaning. 6. No significant change was observed in absolute absorption of glucose or leucine during pregnancy. 7. Absolute absorption of leucine and of glucose was increased during lactation. Greatest absorption occurred on the 10th day of lactation. 8. Results for absorption of leucine and glucose per unit length indicated that the ability of the mucosal cells to absorb or the number of absorptive cells/mm had changed during lactation and the post-lactation periods.