Sensitivity and specificity of the user-seal-check in determining the fit of N95 respirators
Sensitivity and specificity of the user-seal-check in determining the fit of N95 respirators
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DOI：
10.1016/j.jhin.2010.09.034
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发表时间：
2011-03-01
影响因子：
6.9
通讯作者：
Charm, C. Y. C.
中科院分区：
文献类型：
--
作者：
Lam, S. C.;Lee, J. K. L.;Charm, C. Y. C.
世界卫生组织（WHO）和疾病控制和预防中心（CDC）推荐使用N95呼吸机，以防止吸入可能传播呼吸道病原体的飞沫。N95口罩在防止传播方面的可靠性取决于其与佩戴者的贴合度。定量拟合测试（QNFT）是用于客观确定这种拟合的黄金标准。制冷机的制造商还建议进行自我报告的用户密封检查，以检测泄漏。本研究旨在通过研究用户密封检查与QNFT相比的灵敏度和特异性，研究用户密封检查在确定N95呼吸机适配性方面的能力。采用前瞻性和横断面研究设计。对204名中国护理本科生进行了两种常用呼吸机型号（3M 1860 S和3M 1862）的测试。使用Condensation Nucleus Counter Fit测试仪系统将用户密封检查结果与金标准QNFT结果进行比较。计算了使用灭菌器获得的用户密封检查结果的灵敏度和特异性。结果表明，用户密封检查在确定N95散热器的配合方面的敏感性、准确性和预测价值较低。未发现用户密封检查作为QNFT的替代品是可靠的。结果还表明，用户密封检查可能是不可靠的检测总泄漏。我们建议使用QNFT来确定N95散热器的配合。(C)2010年医院感染学会。由爱思唯尔有限公司出版。保留所有权利。
N95 respirators are recommended by the World Health Organization (WHO) and the Centers for Disease Control and Prevention (CDC) to prevent the inhalation of droplets which may transmit respiratory pathogens. The reliability of N95 respirators in preventing transmission depends on their fit to the wearer. Quantitative fit testing (QNFT) is the gold standard used to determine this fit objectively. The manufacturers of the respirators also recommend performing a self-reported user-seal-check to detect for leakage. This study aims to investigate the capability of the user-seal-check in determining the fit of N95 respirators by investigating the sensitivity and specificity of the user-seal-check compared with QNFT. A prospective and cross-sectional research design was used. A total of 204 local Chinese undergraduate nursing students were recruited to test two commonly used respirator models (3M 1860S and 3M 1862). The results of the user-seal-check were compared with the results of the gold standard QNFT using the Condensation Nucleus Counter Fit Tester System. The sensitivity and specificity of the user-seal-check results obtained with the respirators were calculated. The results indicated low sensitivity, accuracy and predictive value of the user-seal-check in determining the fit of the N95 respirators. The user-seal-check was not found to be reliable as a substitute for QNFT. The results also suggested that the user-seal-check may be unreliable for detecting gross leakage. We recommend that QNFT is used to determine the fit of N95 respirators. (C) 2010 The Hospital Infection Society. Published by Elsevier Ltd. All rights reserved.