Biomarkers in COPD
Biomarkers in COPD
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DOI：
10.1016/j.ccm.2013.09.006
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发表时间：
2014-03-01
影响因子：
5.7
通讯作者：
Sin, Don D.
中科院分区：
文献类型：
--
作者：
Agusti, Alvar;Sin, Don D.
慢性阻塞性肺疾病（CORD）是一种异质性疾病，不能仅用气流受限（呼气第一秒用力呼气量）的严重程度来描述。在临床实践中，需要其他措施来评估患者，预测他们的风险，指导他们的治疗，并评估他们对it.In过去几年中，有很大的兴趣在CORD的潜在临床使用的生物标志物的识别和验证。在这里，作者回顾了该领域的一些一般概念，讨论了CORD中目前经过验证的生物标记，并推测了未来的潜在发展。
Chronic obstructive pulmonary disease (CORD) is a heterogeneous disease that cannot be described by the severity of airflow limitation (forced expiratory volume in the first second of expiration) only. Other measures are needed in clinical practice to assess patients, predict their risk, guide their treatment, and assess their response to it. Over the past few years, there has been a great deal of interest in the identification and validation of biomarkers of potential clinical use in CORD. Here, the authors review some general concepts in the field, discuss currently validated bionnarkers in CORD, and speculate on potential future developments.