PREVALENCE OF RIBOFLAVIN DEFICIENCY AMONG GUATEMALAN ELDERLY PEOPLE AND ITS RELATIONSHIP TO MILK INTAKE
PREVALENCE OF RIBOFLAVIN DEFICIENCY AMONG GUATEMALAN ELDERLY PEOPLE AND ITS RELATIONSHIP TO MILK INTAKE
复制标题
DOI：
10.1093/ajcn/58.1.85
复制
发表时间：
1993-07-01
影响因子：
7.1
通讯作者：
RUSSELL, RM
中科院分区：
文献类型：
--
作者：
BOISVERT, WA;CASTANEDA, C;RUSSELL, RM
使用红细胞谷胱甘肽还原酶活性系数（EGRAC）评估了来自危地马拉中部的六组老年受试者的核黄素状态。自由生活的农村老年人核黄素缺乏率为50%～76%。从一些受试者收集的牛奶摄入数据显示，牛奶摄入频率与核黄素状态之间存在显着相关性（P < 0.0001）。在一项短期核黄素补充实验中，9 名核黄素缺乏的受试者每天服用 10 mg 核黄素，持续 3 天，所有受试者的 EGRAC 通过补充均恢复正常。然而，在不补充补充剂的情况下，他们在正常饮食的情况下，在 2 周内就恢复了缺乏状态。危地马拉老年人中核黄素缺乏症的高患病率似乎是由于乳制品等富含核黄素的食物摄入不足造成的，需要定期摄入足够量的核黄素以维持令人满意的核黄素状态。
Six groups of elderly subjects from central Guatemala were assessed for riboflavin status by using the erythrocyte glutathione reductase activity coefficient (EGRAC). The prevalence of riboflavin deficiency ranged from 50% to 76% among the free-living rural elderly subjects. Milk intake data that were collected from some of the subjects showed a significant correlation (P < 0.0001) between frequency of milk intake and riboflavin status. In a short-term riboflavin supplementation experiment in which nine riboflavin-deficient subjects were given 10 mg riboflavin/d for 3 d, all the subjects' EGRACs were normalized by the supplementation. However, they returned to a state of deficiency within 2 wk while consuming their usual diets without supplementation. It appears that the high prevalence of riboflavin deficiency in elderly Guatemalan people is caused by inadequate intake of riboflavin-rich foods such as dairy products, and that sufficient amounts of riboflavin need to be ingested regularly to maintain satisfactory riboflavin status.