Physiological studies of single retinal cells and their morphological identification.
Physiological studies of single retinal cells and their morphological identification.
复制标题
单个视网膜细胞的生理学研究及其形态学鉴定。
DOI：
10.1016/0042-6989(71)90027-7
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发表时间：
1971
期刊：
影响因子：
1.8
通讯作者：
Akimichi Kaneko
中科院分区：
文献类型：
--
作者：
Akimichi Kaneko
Intracellular recordings were made from various types of cells in goldfish retina. Receptive fields of these cells were studied with light spots of different sizes. After recording, the cells were identified morphologically by injecting dyes from the recording electrode: thus correlation was made between cell types and their characteristic responses.Receptors were hyperpolarized by illumination. No obvious spatial summation was seen in these responses. Regardless of wavelength, receptors were always hyperpolarized. They were classified into three types according to response maxima at red, green and blue region of the spectrum. External and internal horizontal cells were identified as the origin ofS-potentials. BothL-andC-typeresponses were seen from two types of horizontal cells. Electrical coupling was demonstrated between neighboring external horizontal cells; presumably this accounts for large spatial summation ofS-potentials. Bipolar cells had center-surround type receptive field. The size of the center was about 100 μ, the same order of magnitude as the dendritic field. The surround was large, extending to about 1.5 mm dia. The majority of bipolar cells were color-coded; in these cells the center always received input from red cones and the surround from green cones. Amacrine cells showed two types of responses, transient and sustained. Their receptive field was at least 2.5 mm dia. All the sustained type amacrine cells showed opponent color responses; hyperpolarization to red and depolarization to green. No spatial segregation was seen between red sensitive and green sensitive areas. It was suggested that a double opponent ganglion cell receives inputs from bipolar cells in the center and from amacrine cells in the surround.
