Gravimetric Analysis of Bismuth in Bismuth Subsalicylate Tablets: A Versatile Quantitative Experiment for Undergraduate Laboratories
Gravimetric Analysis of Bismuth in Bismuth Subsalicylate Tablets: A Versatile Quantitative Experiment for Undergraduate Laboratories
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次水杨酸铋片中铋的重量分析：本科实验室的多功能定量实验
DOI：
10.1021/ed5004614
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发表时间：
2015
影响因子：
3
通讯作者：
Joel Coeler
中科院分区：
文献类型：
--
作者：
E. J. Davis;K. Cheung;Steve Pauls;Jonathan Dick;Elijah B. Roth;N. Zalewski;Christopher Veldhuizen;Joel Coeler
在这个实验室实验中，低年级和高年级的学生将碱式水杨酸铋片溶于酸中，用磷酸钠沉淀溶液中的Bi 3+，以重量法测定片中碱式水杨酸铋的含量。标示浓度为262 mg/片，三个不同疗程（一般化学I和II以及定量分析）的合并数据确定平均片剂浓度为272.0 mg/片，标准差为±48.46 mg。当由高年级学生进行分析时，获得的平均值为268.8 mg/片，标准差为16.02 mg，这证实了标示浓度。此外，学生们有机会将剩余的溶液与铝反应，以减少离子铋并产生固体金属产品，这在一个实验室实验中加强了沉淀，化学计量和还原-氧化的概念。
In this laboratory experiment, lower- and upper-division students dissolved bismuth subsalicylate tablets in acid and precipitated the resultant Bi3+ in solution with sodium phosphate for a gravimetric determination of bismuth subsalicylate in the tablets. With a labeled concentration of 262 mg/tablet, the combined data from three different courses (general chemistry I and II and quantitative analysis) determined an average tablet concentration of 272.0 mg/tablet, with a standard deviation of ±48.46 mg. When analyzed by upper-division students, an average of 268.8 mg/tablet with a standard deviation of 16.02 mg was obtained, which confirmed the labeled concentration. In addition, students were given an opportunity to react the remaining solution with aluminum to reduce the ionic bismuth and produce a solid metal product, which reinforced the concepts of precipitation, stoichiometry, and reduction–oxidation in a single laboratory experiment.