Curvature-Mediated Assembly of Janus Nanoparticles on Membrane Vesicles
Curvature-Mediated Assembly of Janus Nanoparticles on Membrane Vesicles
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DOI：
10.1021/acs.nanolett.7b04855
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发表时间：
2018-02-01
期刊：
影响因子：
10.8
通讯作者：
Weikl, Thomas R.
中科院分区：
文献类型：
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作者：
Bahrami, Amir Houshang;Weikl, Thomas R.
除了直接的粒子粒子相互作用之外，吸附到生物膜上的纳米粒子经历由粒子吸附引起的膜曲率介导的间接相互作用。在这封信中，我们表明，曲率介导的相互作用的吸附Janus粒子依赖于吸附前的膜的初始曲率，也就是说，在我们的模拟中，膜最初是否朝向或远离粒子凸出。曲率介导的相互作用对吸附到膜囊泡外部的Janus颗粒具有强烈的吸引力，膜囊泡最初远离颗粒凸出。相反，对于吸附到囊泡内部的Janus粒子，曲率介导的相互作用是排斥的。我们发现，除了初始膜曲率外，粘附Janus粒子表面的面积分数是曲率介导的粒子相互作用和组装的重要控制参数。
Besides direct particle particle interactions, nanoparticles adsorbed to biomembranes experience indirect interactions that are mediated by the membrane curvature arising from particle adsorption.. In this Letter, we show that the curvature-mediated interactions of adsorbed Janus particles depend on the initial curvature of the membrane prior to adsorption, that is, on whether the membrane initially bulges toward or away from the particles in our simulations. The curvature-mediated interaction Can be strongly attractive for Janus particles adsorbed to the outside of a membrane vesicle, which initially bulges away from the particles. For Janus particles adsorbed to the vesicle inside, in contrast, the curvature-mediated interactions are repulsive. We find that the area fraction of the adhesive Janus particle surface is an important control parameter for the curvature-mediated interaction and assembly of the particle, besides the initial membrane curvature.