INVOLVEMENT OF THE VOMERONASAL ORGAN AND PROLACTIN IN PHEROMONAL INDUCTION OF DELAYED IMPLANTATION IN MICE
INVOLVEMENT OF THE VOMERONASAL ORGAN AND PROLACTIN IN PHEROMONAL INDUCTION OF DELAYED IMPLANTATION IN MICE
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DOI：
10.1530/jrf.0.0590223
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发表时间：
1980-01-01
期刊：
影响因子：
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通讯作者：
KEVERNE, EB
中科院分区：
文献类型：
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作者：
BELLRINGER, JF;PRATT, HPM;KEVERNE, EB
将交配的雌性小鼠暴露在陌生雄性小鼠面前，通过破坏双侧犁鼻器官，显著减少了受孕障碍。用α-溴隐亭治疗新交配的雌性也会产生妊娠障碍。暴露在奇怪的男性气味中的交配雌性也会发生受孕障碍，但未能植入的胚泡仍然存在于子宫中，交配后最长可存活15天。用外源性孕酮和雌二醇诱导小鼠着床。
Pregnancy block caused by exposure of mated female mice to a strange male was significantly reduced by bilateral destruction of the vomeronasal organ. Treatment of newly mated females with .alpha.-bromocriptine also produced pregnancy block. Pregnancy block also occurred in mated females exposed to strange male odors, but the blastocysts which had failed to implant were still present in the uterus and were viable for up to 15 days after mating. Implantation was induced in such mice by administration of exogenous progesterone and estradiol.