Resveratrol supplementation of high‐fat diet‐fed pregnant mice promotes brown and beige adipocyte development and prevents obesity in male offspring
Resveratrol supplementation of high‐fat diet‐fed pregnant mice promotes brown and beige adipocyte development and prevents obesity in male offspring
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DOI：
10.1113/jp273478
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发表时间：
2017-03
期刊：
影响因子：
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通讯作者：
T. Zou;Daiwen Chen;Qiyuan Yang;Bo Wang;Mei-Jun Zhu;P. Nathanielsz;M. Du
中科院分区：
文献类型：
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作者：
T. Zou;Daiwen Chen;Qiyuan Yang;Bo Wang;Mei-Jun Zhu;P. Nathanielsz;M. Du
母体高脂饮食损害棕色脂肪细胞功能，并与后代肥胖相关。母亲白藜芦醇管理恢复后代棕色脂肪组织的代谢活性。母体白藜芦醇促进后代白色脂肪组织中米色脂肪细胞的发育。母体白藜芦醇干预可保护后代免受高脂饮食诱导的肥胖。
Maternal high‐fat diet impairs brown adipocyte function and correlates with obesity in offspring. Maternal resveratrol administration recovers metabolic activity of offspring brown adipose tissue. Maternal resveratrol promotes beige adipocyte development in offspring white adipose tissue. Maternal resveratrol intervention protects offspring against high‐fat diet‐induced obesity.