The minimum information required for reporting a molecular interaction experiment (MIMIx)

The minimum information required for reporting a molecular interaction experiment (MIMIx)
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DOI:
10.1038/nbt1324
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发表时间:
2007-08-01
影响因子:
46.9
通讯作者:
Hermjakob, Henning
Hermjakob, Henning
中科院分区:
工程技术1区
文献类型:
--
作者:
Orchard, Sandra;Salwinski, Lukasz;Hermjakob, Henning

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文献中提供了大量的分子相互作用数据,从大规模数据集到通过几种不同技术证实的单一相互作用。这些数据经常以自由文本或可变格式的表格形式报告,并且经常缺少对于充分理解实验至关重要的关键信息。在这里,我们提出 MIMIx,这是报告分子相互作用实验所需的最少信息。遵守这些报告指南将使出版物对科学界更加清晰和有用,并将支持在公共数据库中快速、系统地捕获分子相互作用数据,从而改善对有价值的相互作用数据的获取。
A wealth of molecular interaction data is available in the literature, ranging from large-scale datasets to a single interaction confirmed by several different techniques. These data are all too often reported either as free text or in tables of variable format, and are often missing key pieces of information essential for a full understanding of the experiment. Here we propose MIMIx, the minimum information required for reporting a molecular interaction experiment. Adherence to these reporting guidelines will result in publications of increased clarity and usefulness to the scientific community and will support the rapid, systematic capture of molecular interaction data in public databases, thereby improving access to valuable interaction data.