Psychological distress following fecal occult blood test in colorectal cancer screening - a population-based study
Psychological distress following fecal occult blood test in colorectal cancer screening - a population-based study
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DOI：
10.3109/00365521.2010.485355
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发表时间：
2010-10-01
影响因子：
1.9
通讯作者：
Jorgensen, Torben
中科院分区：
文献类型：
--
作者：
Brasso, Klaus;Ladelund, Steen;Jorgensen, Torben
目标。评估参与结直肠癌（CRC）筛查项目可能产生的心理副作用。材料和方法。在丹麦的一项CRC筛查可行性研究中，600名参与者被邀请完成一份简短的SCL92（症状检查表）问卷，问卷内容涉及焦虑、抑郁和躯体化领域，并遵循他们的粪便隐血测试结果。3个月和12个月后再次进行问卷调查。结果按年龄、性别及检测结果进行分析。结果。参与率很高，入学时达到84.5%，仅略有下降。这种下降与测试结果或调查问卷的初步结果无关。在进入时，研究人群中每个维度的得分与背景人群的预期得分相似。入学时测试呈阳性的参与者在所有三个领域的得分都明显较高，这种差异在12个月的随访中消失。在3个月和12个月的随访中，男性在所有三个领域的得分都有所下降，而女性仅在焦虑领域得分下降。无论年龄和性别，得分变化的模式都是相同的。无论后来的诊断检查结果如何，测试呈阳性的参与者在随访期间的得分都有所下降。结论。考虑到研究的局限性，结果表明，无论年龄、性别或测试结果如何，CRC筛查后12个月内对心理健康没有不良影响。
Objective. To evaluate the possible psychological side-effect of participating in a colorectal cancer (CRC)-screening program. Materials and methods. Six hundred participants in a Danish CRC screening feasibility study were invited to complete a short version of the SCL92 (symptom check list) questionnaire relating to the domains: anxiety, depression and somatization following information on the result of their fecal occult blood test. The questionnaire was repeated after 3 and 12 months. Results were analyzed according to age, gender and test result. Results. Participation rate was high, 84.5% at entry, and declined only slightly. The decline was not related to test results nor initial results from the questionnaire. At entry, scores in each dimension in the study population were similar to expected scores in the background population. Participants tested positive at entry had significantly higher scores in all three domains, this difference disappeared at 12 months follow-up. Men had declining scores in all three domains at 3 and 12 months follow-up, whereas women had declining scores only in the domain anxiety. Identical patterns in changes in scoring were found regardless of age and gender. Participants tested positive had, regardless of later results of diagnostic work-up, declining scores during follow-up. Conclusions. Given the limitations of the study, the results demonstrate no adverse effect on psychological well-being within 12 months following CRC screening regardless of age, gender or test result.