Anomalous left coronary artery from pulmonary artery (ALCAPA) in infants: a 5-year review in a defined birth cohort
Anomalous left coronary artery from pulmonary artery (ALCAPA) in infants: a 5-year review in a defined birth cohort
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DOI：
10.1007/s00431-007-0423-1
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发表时间：
2008-01-01
影响因子：
3.6
通讯作者：
Philip, Roy K.
中科院分区：
文献类型：
--
作者：
Brotherton, Helen;Philip, Roy K.
异常左冠状动脉起源于肺动脉是一种罕见的先天性心脏畸形。它主要出现在婴儿期，以心肌缺血或心力衰竭为特征，可能被误认为常见的儿科疾病，如绞痛、反流或细支气管炎。早期手术矫正预后良好，但对这种情况的认识是必要的，以及时诊断和转诊到三级心脏中心。在这份报告中，我们回顾了我们5年研究期间的5例病例，并讨论了婴儿ALCAPA的发病率和临床表现。我们观察到的发病率为1/4243活产-0.023%-高于以前的报告。ALCAPA可能比以前认识到的更常见，儿科医生，儿科实习生和全科医生应该有很高的认识指数，以便早期手术干预和改善这些儿童的预后。
Anomalous left coronary artery from pulmonary artery (ALCAPA) is a rare congenital cardiac malformation. It presents predominantly in infancy with features of myocardial ischaemia or cardiac failure and may be mistaken for common paediatric conditions such as colic, reflux or bronchiolitis. With early surgical correction the prognosis is good, but awareness of this condition is essential for prompt diagnosis and referral to a tertiary cardiac centre. In this report we review the five cases that presented during our 5-year study period and discuss the incidence and clinical presentation of ALCAPA among infants. Our observed incidence of 1 in 4243 live births - 0.023 % - is higher than previously reported. ALCAPA may be more common than previously recognised, and there should be a high index of awareness among paediatricians, paediatric trainees and general practitioners to enable early surgical intervention and improved prognosis for these children.