MECHANICAL PERFORMANCE OF PLLA STENT.
MECHANICAL PERFORMANCE OF PLLA STENT.
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PLA 支架的机械性能。
DOI：
10.1115/dmd2018-6957
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发表时间：
2018
期刊：
影响因子：
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通讯作者：
Gu,Linxia
中科院分区：
文献类型：
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作者：
Wang,Longzhen;Tong,Junfei;Dong,Pengfei;Wilson,DavidL;Bezerra,HiramG;Gu,Linxia
支架植入被广泛用于治疗管腔阻塞。支架是由聚合物和金属合金（包括不锈钢、钴铬和镍钛诺[1]）制成的网状结构。临床研究表明，当组织适应支架环境时，支架有助于支撑病变病变长达一年。然而，动脉内永久植入支架存在支架断裂、组织炎症、支架内再狭窄、血栓形成等并发症。目前，可生物降解支架因其治疗管腔阻塞的潜在长期疗效而受到越来越多的关注。生物可降解支架的详细特征对预期的临床结果至关重要。
Stent implantation is widely used to treat blocked lumen. Stents were meshed structure made of polymers and metal alloys, including stainless steel, cobalt chrome and nitinol [1]. Clinical studies had demonstrated that stents helped to scaffold the diseased lesion up to one year when tissue adapted to the stented environment [2]. However, the permanently implanted stents inside artery were associated with complications such as stent fracture, tissue inflammation, in-stent restenosis and thrombosis [3]. Currently, biodegradable stents are attracting more attention due to its potential long-term efficacy in treating blocked lumens. The detailed characterizations of biodegradable stents are essential for the desired clinical outcomes.