A role for secretory phospholipase A(2) and C-reactive protein in the removal of injured cells

A role for secretory phospholipase A(2) and C-reactive protein in the removal of injured cells
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DOI:
10.1016/s0167-5699(97)01002-5
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发表时间:
1997-03-01
期刊:
IMMUNOLOGY TODAY
影响因子:
--
通讯作者:
vandenBosch, H
vandenBosch, H
中科院分区:
其他
文献类型:
--
作者:
Hack, CE;Wolbink, GJ;vandenBosch, H

文献摘要

被引文献

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急性期反应是对感染或物理创伤的反应,其特征是某些血浆蛋白水平的增加。在这里,Erik Hack及其同事认为,这些急性期蛋白中的两种,分泌型磷脂酶A(2)和C反应蛋白的联合作用可能有助于促进对受损细胞和组织碎片的吞噬作用,从而增强炎症和组织损伤。
The acute phase response is initiated in response to infection or physical trauma and is characterized by an increase in the levels of some plasma proteins. Here, Erik Hack and colleagues suggest that the combined actions of two of these acute phase proteins, secretory phospholipase A(2) and C-reactive protein, may serve to promote phagocytosis of injured cells and tissue debris, thereby enhancing inflammation and tissue damage.