Antibody Levels to Herpes Simplex Type 1, Measles and Rubella Viruses in Psychiatric Patients

Antibody Levels to Herpes Simplex Type 1, Measles and Rubella Viruses in Psychiatric Patients
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精神病患者中 1 型单纯疱疹病毒、麻疹和风疹病毒的抗体水平

DOI:
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发表时间:
1974
影响因子:
10.5
通讯作者:
V. Jäntti
V. Jäntti
中科院分区:
医学1区
文献类型:
--
作者:
P. Halonen;R. Rimón;Katve Arohonka;V. Jäntti

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对各种进展缓慢的或亚急性神经系统疾病的病原体的系统搜索发现了库鲁病、克雅氏病和其他形式的老年前痴呆、亚急性硬化性全脑炎、进行性多灶性脑病以及动物中许多类似的神经系统疾病的病原体或病毒样病原体(Gajdusek和Gibbs,1973;Gajdusek,1973)。前两种疾病称为亚急性海绵状病毒脑病(Gajdusek和Gibbs,1971),具有许多有趣的特征,包括家族性发生和完全非炎症性神经病理。因此,这些疾病的流行病学不是典型的感染性病因学疾病,组织病理学研究也不表明脑细胞中存在极高滴度的感染性物质。
The systematic search of aetiological agents from a variety of slowly progressing or subacute neurological diseases has revealed causative viruses or virus-like agents from kuru, Creutzfeldt-Jacob disease and other forms of presenile dementias, subacute sclerosing panencephalitis, progressive multifocal encephalopathy, and from many similar neurological diseases in animals (Gajdusek and Gibbs, 1973; Gajdusek, 1973). The first two diseases called subacute spongiform virus encephalopathies (Gajdusek and Gibbs, 1971) have many interesting features including heredo-familial occurrence and totally non-inflammatory neuropathology. Thus the epidemiology of these diseases is not typical for diseases with infectious aetiology, and the histopathological studies do not suggest the presence of extremely high-titred infectious material in brain cells.