Double emulsion templated microcapsules with single hollow cavities and thickness-controllable shells.
Double emulsion templated microcapsules with single hollow cavities and thickness-controllable shells.
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DOI：
10.1021/la804173b
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发表时间：
2009-02
期刊：
影响因子：
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通讯作者：
Fei Gao;Z. Su;Ping Wang;G. Ma
中科院分区：
文献类型：
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作者：
Fei Gao;Z. Su;Ping Wang;G. Ma
采用两步乳化、乳液熟化和悬浮聚合法制备了一种具有单空腔、壳层厚度可控的新型微胶囊。本研究重点研究了水包油包水（W/O/W）乳液微球的形貌控制参数，提出了一种由多核前驱体制备单核油包水（W/O）微球的通用策略。这些单核球进一步被用作固体微胶囊的模板通过悬浮聚合，在此期间，相分离机制可以用来形成纳米通道的外壳。这种微胶囊可以进一步开发为具有待装载的功能核的微反应器，并且将特别适合于笼封生物活性材料。
A novel form of microcapsules, which possess single hollow cavities and thickness-controllable shells, were prepared by a two-step emulsification, emulsion ripening, and suspension polymerization. Parameters on morphology control of water-in-oil-in-water (W/O/W) emulsion globules were particularly investigated in this study, and a universal strategy to prepare single-core water-in-oil (W/O) globules from their multicore precursors was proposed. These single-core globules were further utilized as templates for solid microcapsules by the suspension polymerization, during which the phase-separation mechanism could be employed to form nanochannels across the shells. Such microcapsules could be further exploited as microreactors with functional cores to be loaded and would be especially suitable to encage bioactive materials.