Prevalence and type spectrum of human papillomaviruses in healthy skin samples collected in three continents
Prevalence and type spectrum of human papillomaviruses in healthy skin samples collected in three continents
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DOI：
10.1099/vir.0.18836-0
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发表时间：
2003-07-01
影响因子：
3.8
通讯作者：
Hansson, BG
中科院分区：
文献类型：
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作者：
Antonsson, A;Erfurt, C;Hansson, BG
为了调查之前在白种人中普遍存在的皮肤乳头瘤病毒感染的发现是否适用于世界其他地区的人群，我们将孟加拉国、日本、埃塞俄比亚和赞比亚的皮肤拭子样本与瑞典的样本同时进行了分析。来自孟加拉国、日本、埃塞俄比亚、赞比亚和瑞典的HPV DNA感染率分别为68%、54%、52%、42%和70%。在142个HPV dna阳性样本中发现了88种HPV型或推定型，证明了基因型的巨大多样性。在同一样本中经常发现双重或多重基因型。最流行的HPV类型是HPV-5，总体患病率为6.5%。这也是在研究中所有国家的样本中发现的唯一类型。结果表明，共生皮肤HPV感染具有世界范围的分布，具有非常广泛的基因型。
In order to investigate whether previous findings of ubiquitous skin papillomavirus infection in Caucasians apply to populations from other parts of the world, skin swab samples from Bangladesh, Japan, Ethiopia and Zambia were analysed in parallel with Swedish samples. The prevalence of HPV DNA in the material from Bangladesh was 68 %, Japan 54 %, Ethiopia 52 %, Zambia 42 % and Sweden 70 %. A great multiplicity of genotypes was demonstrated by the finding of 88 HPV types or putative types in 142 HPV DNA-positive samples in total. Double or multiple genotypes were frequently found in the same sample. The most prevalent HPV type was HPV-5, with an overall prevalence of 6.5 %. This was also the only type that was found in samples from all of the countries in the study. The results presented show that commensal skin HPV infections have a worldwide distribution with a very broad spectrum of genotypes.