Skin perfusion evaluation between laser speckle contrast imaging and laser Doppler flowmetry
Skin perfusion evaluation between laser speckle contrast imaging and laser Doppler flowmetry
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DOI：
10.1016/j.optcom.2012.11.054
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发表时间：
2013-03-15
影响因子：
2.4
通讯作者：
Abraham, Pierre
中科院分区：
文献类型：
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作者：
Humeau-Heurtier, Anne;Mahe, Guillaume;Abraham, Pierre
在生物医学领域，激光多普勒血流测量（LDF）和激光散斑对比成像（LSCI）是两种旨在无创监测微血管血流灌注的光学技术。LDF已经使用了近40年，而LSCI是一种最近的技术，克服了LDF的一些缺点。LDF和LSCI均给予任意单位的灌注评估。然而，LDF灌注与LSCI大血流值之间可能存在的关系尚未完全研究。因此，我们在此评估LDF和LSCI灌注值在广泛的皮肤血流范围之间的关系。为此，在12名健康受试者的前臂上，在不同的血管闭塞持续时间和反应性充血期间，同时获得LDF和LSCI数据。对于研究的皮肤血流范围，幂函数比线性函数更适合数据：单个受试者的幂在1.2到1.7之间，当所有受试者一起研究时，幂函数接近1.3。因此，我们建议区分两种光学系统给出的灌注值。(C) 2012 Elsevier B.V.版权所有
In the biomedical field, laser Doppler flowmetry (LDF) and laser speckle contrast imaging (LSCI) are two optical techniques aiming at monitoring - non-invasively - the microvascular blood perfusion. LDF has been used for nearly 40 years whereas LSCI is a recent technique that overcomes some drawbacks of LDF. Both LDF and LSCI give perfusion assessments in arbitrary units. However, the possible relationship existing between perfusions given by LDF and by LSCI over large blood flow values has not been completely studied yet. We therefore herein evaluate the relationship between the LDF and LSCI perfusion values across a broad range of skin blood flows. For this purpose, LDF and LSCI data were acquired simultaneously on the forearm of 12 healthy subjects, at rest, during different durations of vascular occlusion and during reactive hyperemia. For the range of skin blood flows studied, the power function fits the data better than the linear function: powers for individual subjects go from 1.2 to 1.7 and the power is close to 1.3 when all the subjects are studied together. We thus suggest distinguishing perfusion values given by the two optical systems. (C) 2012 Elsevier B.V. All rights reserved.