Variability of diabetic macular edema in correlation with hypertension retinopathy in patients with diabetes mellitus and essential hypertension
Variability of diabetic macular edema in correlation with hypertension retinopathy in patients with diabetes mellitus and essential hypertension
复制标题
糖尿病合并原发性高血压患者糖尿病黄斑水肿与高血压视网膜病变相关性的变异性
DOI：
10.22336/rjo.2019.52
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发表时间：
2019
期刊：
影响因子：
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通讯作者：
D. Moraru
中科院分区：
文献类型：
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作者：
D. Stana;V. Potop;Sinziana Istrate;Cecilia Eniceicu;A. Mihalcea;Irena Gabriela Pașca;Abdallah Aqel;R. Ciuluvică;D. Moraru
Objective.本研究旨在确定2型糖尿病患者高血压视网膜病变相关的糖尿病黄斑水肿变异性与原发性高血压之间的可能关系，以及与对比敏感度的相关性。材料与方法。为了实现这一目标，本回顾性研究通过使用光学相干断层扫描测量黄斑总体积和中央黄斑厚度，并通过Pelli Robson测试测量对比敏感度变化，每天沿着血压和血压测量，评估白天高血压患者糖尿病黄斑水肿的进展。结果我们的研究结果显示，在每一个测试小时，黄斑中心厚度和黄斑厚度之间的对比敏感度值之间的相关性具有统计学意义。结论.该研究揭示了许多统计学上显著的相关性，包括血压、血糖水平、Pelli Robson测试和中央黄斑厚度。缩略语：OCT =光学相干断层扫描; DME =糖尿病黄斑水肿; SD-OCT =光谱域光学相干断层扫描; LOCS =透镜混浊分类系统; LE =左眼; ANOVA =方差分析
Objective. This study aimed to determine the possible relationship between variability of diabetic macular edema associated with hypertension retinopathy in patients with type 2 diabetes mellitus and essential high blood pressure, in correlation with contrast sensitivity. Material and Methods. In order to accomplish the objective, this retrospective study evaluated the progression of diabetic macular edema in patients with high blood pressure during day time through measurements of the total macular volume and central macular thickness using optical coherence tomography and contrast sensitivity variations measured through Pelli Robson test, four times a day, along with glycemia and blood pressure measurements. Results. Our results showed a statistically significant correlation between the values of glycemia and central macular thickness, and between contrast sensitivity and macular thickness at every tested hour. Conclusions. The study revealed many statistically significant correlations involving blood pressure, blood glucose levels, Pelli Robson test and central macular thickness. Abbreviations: OCT = optical coherence tomography; DME = diabetic macula edema; SD-OCT = spectral domain optical coherence tomography; LOCS = lens opacities classification system; LE = left eye; ANOVA = analysis of variance