Improving effect of dietary soybean phospholipids supplement on hepatic and serum indexes relevant to fatty liver hemorrhagic syndrome in laying hens
Improving effect of dietary soybean phospholipids supplement on hepatic and serum indexes relevant to fatty liver hemorrhagic syndrome in laying hens
复制标题
日粮添加大豆磷脂对蛋鸡脂肪肝出血综合征相关肝脏及血清指标的改善作用
DOI：
10.1111/asj.12832
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发表时间：
2017
影响因子：
2
通讯作者：
Hu Guoliang
中科院分区：
文献类型：
--
作者：
Yang Fei;Ruan Jiming;Wang Tiancheng;Luo Junrong;Cao Huabin;Song Yalu;Huang Jianzhen;Hu Guoliang
为研究饲粮中添加大豆磷脂对蛋鸡肝脏及与脂肪肝出血综合征（FLHS）相关的血清指标的影响，试验选用135只300日龄海兰褐蛋鸡，随机分为3组（对照组、病理组和预防组），每组45只，每组3个重复。3组分别饲喂添加3%大豆磷脂代替玉米的对照饲粮、高能量低蛋白饲粮和高能量高蛋白饲粮。结果显示，在第30天，病理组的肝脏变黄、变大并出现出血点，而预防组和对照组的肝脏未出现此类病理变化。预防组和对照组血清或肝脏匀浆中甘油三酯、总胆固醇、低密度脂蛋白-胆固醇、非酯化脂肪酸和丙二醛含量显著或极显著低于病理组（P< 0.05或P< 0.01），谷草转氨酶和谷丙转氨酶活性显著或极显著低于病理组（P< 0.01）；高密度脂蛋白-胆固醇值明显高于病理组（P< 0.01）。提示饲粮中添加大豆磷脂可有效改善与FLHS相关的肝脏和血液指标，为预防蛋鸡FLHS的发生和治疗人类非酒精性脂肪肝提供了新的切入点。
In order to investigate the effect of dietary soybean phospholipid supplement on hepatic and serum indexes relevant to fatty liver hemorrhagic syndrome (FLHS) in layers, 135 300‐day‐old Hyline Brown layers were randomly divided into three groups (control, pathology and prevention), and each group had 45 layers with three replicates. Birds in the three groups were respectively fed the control diet, high‐energy low‐protein diet and high‐energy high‐protein diet affixed with 3% soybean phospholipid instead of maize. Results showed in the 30th day, birds’ livers in the pathology group became yellowish, enlarged in size and had hemorrhagic spots, while the prevention and control groups’ layers did not have such pathological changes. Contents of triglyceride, total cholesterol, low‐density lipoprotein – cholesterol, non‐esterified fatty acid and malondialdehyde in serum or liver homogenate in prevention and control groups were remarkably lower than those in the pathology group (P< 0.05 orP< 0.01), as with the activities of glutamic oxalacetic transaminase and glutamic‐pyruvic transaminase (P< 0.01); high‐density lipoprotein – cholesterol value was strikingly higher than that of the pathology group (P< 0.01). It is suggested dietary soybean phospholipids supplement may effectively improve hepatic and blood indexes relevant to FLHS, which provides a new point for preventing FLHS occurrence rate in laying flocks and treating human non‐alcohol fatty liver disease.