Recent Advances in Endometrial Cancer.
Recent Advances in Endometrial Cancer.
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DOI：
10.12688/f1000research.10020.1
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发表时间：
2017
期刊：
影响因子：
--
通讯作者：
Gehrig P
中科院分区：
文献类型：
--
作者：
Tran AQ;Gehrig P
子宫内膜癌是美国最常见的妇科恶性肿瘤，每年的发病率持续上升。大多数妇女目前与早期阶段的疾病;然而，先进的疾病进行了严重的预后。因此，目前正在研究用于治疗子宫内膜癌的新疗法。这些进展包括更好地了解子宫内膜癌发生的遗传基础，新的手术疗法以及治疗这种疾病的新分子靶点。本文综述了有关子宫内膜癌的这些进展的文献。
Endometrial cancer is the most common gynecologic malignancy in the United States, with yearly rates continuing to increase. Most women present with early stage disease; however, advanced disease carries a grave prognosis. As a result, novel therapies are currently under investigation for the treatment of endometrial cancer. These advances include a better understanding of the genetic basis surrounding the development of endometrial cancer, novel surgical therapies, and new molecular targets for the treatment of this disease. This review explores the literature regarding these advancements in endometrial cancer.