Cardiovascular risk factors in children and adolescents with anxiety disorders and their association with disease severity
Cardiovascular risk factors in children and adolescents with anxiety disorders and their association with disease severity
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DOI：
10.3305/nh.2015.31.1.7523
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发表时间：
2015-01-01
期刊：
影响因子：
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通讯作者：
Bosa, Vera Lúcia
中科院分区：
文献类型：
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作者：
Cheuiche Pires, Gabriela;Camboim Rockett, Fernanda;Bosa, Vera Lúcia
研究表明，焦虑是不良心血管事件的独立预测因子。然而，很少有研究调查心血管危险因素（RF）与儿童和青少年焦虑症（AD）严重程度之间的关系。目的：评估患有焦虑症的儿童和青少年心血管RF的患病率及其与疾病严重程度的关系。方法：采用横断面研究评估儿童和青少年焦虑症的营养和人体测量RE、体脂率（BF）、血压（BP）、体力活动水平、焦虑症状和严重程度。结果：共有65名儿童和青少年（8.6±1.7岁）参加了研究。饱和脂肪酸摄入过多（52.3%）、高体重指数（50.8%）、高血压（50.8%）和缺乏身体活动（50.0%）是最常见的心血管RF。焦虑的严重程度与>= 6rf /患者（p=0.026）、腹部多余体脂（以腰围衡量）（p=0.019）和锥度指数（p= 0.053）以及多余% BF （p=0.035）之间存在显著关联。广泛性焦虑障碍与高血压显著相关（p=0.044）。结论：在本样本中发现心血管RF的患病率较高，并且焦虑越严重的个体心血管风险越大。年轻人群的心血管风险特征，特别是阿尔茨海默病患者更容易患心血管疾病，对于这些患者生活方式干预的发展至关重要。
Introduction: Studies suggest that anxiety is an independent predictor of adverse cardiovascular events. However, few studies have investigated the association between cardiovascular risk factors (RF) and severity of anxiety disorders (AD) in childhood and adolescents.Objectives: To assess the prevalence of cardiovascular RF in children and adolescents with anxiety disorders and their association with disease severity.Method: Cross-sectional study assessing nutritional and anthropometric RE, as well as % body fat (BF), blood pressure (BP), physical activity level, anxiety symptoms and severity of the anxiety disorder of children and adolescents.Results: A total of 65 children and adolescents (8.6 +/- 1.7 years) took part in the study. Excess saturated fatty acid intake (52.3%), high body mass index (50.8%), high BP (50.8%) and physical inactivity (50.0%) were the most prevalent cardiovascular RF. There was a significant association between the severity of the anxiety and the presence of >= 6 RF per patient (p=0.026), excess abdominal body fat as assessed by waist circumference (p=0.019) and conicity index (p=0,053), and excess % BF (p=0.035). Generalized anxiety disorder was significantly associated with high BP (p=0.044).Conclusion: A high prevalence of cardiovascular RF was found in the present sample, and individuals with more severe anxiety had greater cardiovascular risk. The characterization of the cardiovascular risk in young populations, especially in individuals with AD who are therefore more susceptible to CVD, is crucial for the development of lifestyle interventions in these patients.