Ovarian cancer screening in the general population: current status
Ovarian cancer screening in the general population: current status
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DOI：
10.1046/j.1525-1438.2001.11(suppl.1)sup1003.x
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发表时间：
2001-01-01
影响因子：
4.8
通讯作者：
Jacobs, IJ
中科院分区：
文献类型：
--
作者：
Menon, U;Jacobs, IJ
通过筛查普通人群中的无症状妇女来早期发现卵巢癌的前景已经引起了相当大的兴趣。最近发表的试验结果提供了关于可能对死亡率产生影响的令人鼓舞的数据。然而，对于筛查假阳性结果的手术依从性、费用和发病率，人们存在担忧。在美国和英国进行的两项随机对照试验旨在明确确定筛查对卵巢癌死亡率的真正影响，同时全面解决筛查的目标人群、依从性、健康经济学和生理和心理发病率等问题。
There has been considerable interest in the prospect of early detection of ovarian cancer through screening asymptomatic women from the general population. The results of recently published trials provide encouraging data on the possible impact on mortality. There are, however, concerns about compliance, cost, and morbidity from surgery for false positive screen results. The two ongoing randomized controlled trials in the US and UK aim to establish definitively the true impact of screening on ovarian cancer mortality while comprehensively tackling the issues of target population, compliance, health economics, and physical and psychological morbidity of screening.