Testing the effectiveness of a motivational interviewing-based brief intervention for substance use as an adjunct to usual care in community-based AIDS service organizations: study protocol for a multisite randomized controlled trial
Testing the effectiveness of a motivational interviewing-based brief intervention for substance use as an adjunct to usual care in community-based AIDS service organizations: study protocol for a multisite randomized controlled trial
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DOI：
10.1186/s13722-017-0095-8
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发表时间：
2017-11-17
影响因子：
3.7
通讯作者：
Martino, Steve
中科院分区：
文献类型：
--
作者：
Garner, Bryan R.;Gotham, Heather J.;Martino, Steve
背景：2010年，美国发布了第一个全面的国家艾滋病毒/艾滋病战略，其中包括三个目标：(1)减少艾滋病毒感染者的人数，(2)增加艾滋病毒感染者获得护理的机会，改善艾滋病毒感染者的健康状况，(3)减少与艾滋病毒有关的健康差距和健康不平等现象。2013年，作为帮助解决国家艾滋病毒/艾滋病战略的努力的一部分，国家药物滥用问题研究所资助了一项名为药物滥用治疗到艾滋病毒护理(SAT2HIV)项目的第二类有效性-实施混合试验。SAT2HIV项目的目标1测试以激励访谈为基础的短暂干预(MIBI)的有效性，作为其MIBI实验的一部分，在艾滋病服务组织(ASOS)内将物质使用作为日常护理的辅助手段。SAT2HIV项目的目标2测试实施和维持便利(ISF)作为成瘾技术转移中心(ATTC)模式的辅助工具的有效性，作为其ISF实验的一部分，培训工作人员进行激励性面谈。本文描述了ISF实验的研究方案。方法：作为多点随机对照试验的一部分，患有HIV/AIDS并有问题药物使用的个体被随机分为两组，分别接受ASO的常规护理(对照条件)或常规护理加MIBI药物使用(实验条件)，由受过培训的ASO病例管理人员提供。主要结果指标是主要物质使用天数的减少，与物质相关的问题的数量，从事危险行为的次数，不坚持艾滋病毒药物治疗的天数，以及物质使用治疗的增加。作为本文的一部分，我们根据标准议定书项目：介入试验建议指南来描述试验方案。讨论：如果能够成功地实施MIBI作为常规护理的有效辅助，本试验可能对提高ASO解决艾滋病毒/艾滋病患者使用问题物质的能力产生重大影响。减少美国境内艾滋病毒/艾滋病患者使用有问题物质的流行率可能会导致关键业绩衡量标准(即艾滋病毒护理连续体和90-90-90目标)的显著改进。
Background: In 2010, the first comprehensive National HIV/AIDS Strategy for the United States was released and included three goals: (1) reducing the number of people who become infected with HIV, (2) increasing access to care and improving health outcomes for people living with HIV, and (3) reducing HIV-related health disparities and health inequities. In 2013, as part of its effort to help address the National HIV/AIDS Strategy, the National Institute on Drug Abuse (NIDA) funded a type 2 effectiveness-implementation hybrid trial titled the Substance Abuse Treatment to HIV Care (SAT2HIV) Project. Aim 1 of the SAT2HIV Project tests the effectiveness of a motivational interviewing-based brief intervention (MIBI) for substance use as an adjunct to usual care within AIDS Service Organizations (ASOs) as part of its MIBI Experiment. Aim 2 of the SAT2HIV Project tests the effectiveness of implementation and sustainment facilitation (ISF) as an adjunct to the Addiction Technology Transfer Center (ATTC) model for training staff in motivational interviewing as part of its ISF Experiment. The current paper describes the study protocol for the ISF Experiment.Methods: As part of a multisite randomized controlled trial, individuals with comorbid HIV/AIDS and problematic substance use are randomized to receive either the ASOs' usual care (control condition) or usual care plus a MIBI for substance use (experimental condition) delivered by trained ASO case-management staff. Primary outcome measures are reductions in days of primary substance use, number of substance-related problems, times engaging in risky behaviors, days of non-adherence to HIV medications, and increases in substance use treatment. As part of this paper, we describe the trial protocol in accordance with the Standard Protocol Items: Recommendations for Interventional Trials guidelines.Discussion: If successfully able to implement MIBI as an effective adjunct to usual care, the current trial may have a significant impact on increasing the capacity of ASOs to address problematic substance use among individuals living with HIV/AIDS. Reducing the prevalence of problematic substance use among individuals living with HIV/AIDS within the United States may lead to significant improvements on key performance measures (i.e., the HIV Care Continuum and the 90-90-90 target).