Biological and corrosion behavior of m-ZrO2 and t-ZrO2 coated 316L SS for potential biomedical applications
Biological and corrosion behavior of m-ZrO2 and t-ZrO2 coated 316L SS for potential biomedical applications
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DOI：
10.1016/j.ceramint.2018.05.103
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发表时间：
2018-08-15
影响因子：
5.2
通讯作者：
Kirubaharan, A. M. Kamalan
中科院分区：
文献类型：
--
作者：
Kaliaraj, Gobi Saravanan;Vishwakarma, Vinita;Kirubaharan, A. M. Kamalan
表面改性是生物医学领域中一项公认的改善植入材料性能的技术。本研究采用电子束物理气相沉积技术(EBPVD)在不锈钢(316L不锈钢)上沉积了单斜相(m-ZrO2)和四方相(t-ZrO2)相，以提高衬底材料的各项性能。M-ZrO2和t-ZrO2涂层有效地保护了细菌对致病性铜绿假单胞菌的入侵和随后的生物被膜形成。M-ZrO2和t-ZrO2涂层的成纤维细胞存活率较高，细胞铺展能力增强。此外，电化学阻抗谱(EIS)结果显示，m-ZrO2和t-ZrO2涂层的电荷转移电阻(R-ct)增强，从而大大改善了涂层在人工血浆(ABP)中的防腐蚀性能。
Surface modification is an established technology in biomedical industries to improve the performance of implant materials. In the present study, monoclinic (m-ZrO2) and tetragonal (t-ZrO2) phases of zirconia were deposited on stainless steel (316L SS) by electron beam physical vapor deposition (EBPVD) to enhance several properties of substrate material. m-ZrO2 and t-ZrO2 coatings effectively protected bacterial invasion against pathogenic Pseudomonas aeruginosa (P. aeruginosa) and subsequent biofilm formation. Superior fibroblast cell viability with improved cells spreading was observed in m-ZrO2 and t-ZrO2 coatings. Furthermore, electrochemical impedance spectroscopy (EIS) results exhibited enhanced charge transfer resistance (R-ct) and thus, strongly improved corrosion protection by m-ZrO2 and t-ZrO2 coatings compared to bare 316L SS substrate in artificial blood plasma (ABP).