Patient-Reported Outcomes Measurement Information System (PROMIS) Global Health Short Forms Demonstrate Responsiveness in Patients Undergoing Knee Arthroplasty
Patient-Reported Outcomes Measurement Information System (PROMIS) Global Health Short Forms Demonstrate Responsiveness in Patients Undergoing Knee Arthroplasty
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DOI：
10.1016/j.arth.2020.01.032
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发表时间：
2020-06-01
影响因子：
3.5
通讯作者：
Banka, Trevor R.
中科院分区：
文献类型：
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作者：
Khalil, Lafi S.;Darrith, Brian;Banka, Trevor R.
背景：患者报告结局测量信息系统（PROMIS）是传统结局指标的替代方案。我们调查了膝关节置换术患者的膝关节损伤和骨关节炎结局评分（KOOS-JR）与PROMIS全球健康身体健康（PH）和心理健康（MH）表格之间的关系。方法：这是一项回顾性队列研究，研究对象为2017年12月至2019年4月的膝关节置换术患者，他们在术前和术后收集了调查。我们排除了接受翻修手术的患者。结果评分进行了分析，反应性，效果大小指数（ESI），最小临床重要差异（MCID），并通过12个月后相互关联。PROMIS-PH的地板效应和天花板效应均为0%。术后PROMIS-PH和KOOS-JR评分彼此显著相关，并且在每个术后时间点均较基线增加（均P <0.001）。PROMIS-MH在时间点之间没有变化（P> 0.05）。PROMIS-PH在1个月和3个月时显示出中度反应性（ESI >0.2），在6个月和12个月时显示出极好的反应性（ESI >0.8），而KOOS-JR在所有时间点均显示出反应性（ESI >0.8）。PROMIS-PH的MCID与KOOS-JR显著相关，术前PROMIS-PH评分小于32.5预测实现MCID，特异性为97%。结论：PROMIS全球健康表格是一个有效的指标，它捕获患者的结果，并与KOOS-JR评分膝关节置换术后。虽然KOOS-JR在术后早期可能更敏感，但两项指标在膝关节置换术后6个月和12个月均显示出极佳的反应性。(C)2020爱思唯尔公司All rights reserved.
Background: The Patient-Reported Outcomes Measurement Information System (PROMIS) is an alternative to legacy outcome metrics. We investigated the relationship between Knee Injury and Osteoarthritis Outcomes Score for Joint Replacement (KOOS-JR) and PROMIS Global Health forms of Physical Health (PH) and Mental Health (MH) in knee arthroplasty patients.Methods: This is a retrospective cohort study of knee arthroplasty patients from December 2017 through April 2019 who had surveys collected preoperatively and postoperatively. We excluded patients undergoing revision surgery. Outcome scores were analyzed for responsiveness, effect size index (ESI), minimal clinically important difference (MCID), and correlation with each other through 12 months postoperatively.Results: A total of 875 patients were included. Floor and ceiling effects were 0% for PROMIS-PH. Postoperative PROMIS-PH and KOOS-JR scores significantly correlated with one another and increased from baseline at each postoperative time point (P < .001 for all). PROMIS-MH did not change between time points (P> .05). PROMIS-PH showed moderate responsiveness at 1 and 3 months (ESI >0.2) and excellent responsiveness at 6 and 12 months (ESI >0.8), whereas KOOS-JR was responsive at all time points (ESI >0.8). The MCID of PROMIS-PH correlated significantly with KOOS-JR, and a preoperative PROMIS-PH score of less than 32.5 predicted achieving MCID with 97% specificity.Conclusion: PROMIS global health forms are a valid metric which capture patient outcomes and correlate with KOOS-JR scores after knee arthroplasty. Although KOOS-JR may be more responsive in the early postoperative time period, both measures show excellent responsiveness at 6 and 12 months after knee arthroplasty. (C) 2020 Elsevier Inc. All rights reserved.