The Familial Occurrence of Agoraphobia

The Familial Occurrence of Agoraphobia
复制标题

广场恐惧症的家族发生率

DOI:
--
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发表时间:
1985
影响因子:
10.5
通讯作者:
G. Andrews
G. Andrews
中科院分区:
医学1区
文献类型:
--
作者:
C. Moran;G. Andrews

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摘要 广场恐惧症被认为是有家族遗传性的,但这种观点并没有得到文献的充分支持。收集了 60 名广场恐惧症先证者的父母和兄弟姐妹患广场恐惧症风险的数据;据报道,12.5% 的亲属患有或曾经患有广场恐惧症。这种风险明显大于人群发病率的估计,需要解释。谱系的细节并不直接支持简单的遗传模型,而其他研究人员对广场恐惧症的环境因素的调查尚未得出结论。由于广场恐惧症存在家族性,因此需要开展进一步的工作来阐明遗传因素还是文化因素是否最重要
Summary Agoraphobia is believed to run in families, but this belief is not well supported by the literature. Data were gathered on the risk of agoraphobia in parents and siblings of 60 agoraphobic probands; 12½% of the relatives were reported to have or have had agoraphobia. This risk is significantly greater than estimates of the population incidence, and requires explanation. The details of the pedigrees do not directly support simple genetic models while investigations into environmental factors in agoraphobia by other workers have been inconclusive. As a putative case has been established for the familial occurrence of agoraphobia, further work is required to shed light on whether genetic or cultural factors are paramount
DOI: 10.1001/archpsyc.1982.04290010031006
发表时间: 1982
影响因子: --
作者:
Thompson,WD;Orvaschel,H;Prusoff,BA;Kidd,KK
通讯作者: Kidd,KK