Increased HIV diagnoses in West Virginia counties highly vulnerable to rapid HIV dissemination through injection drug use: a cautionary tale
Increased HIV diagnoses in West Virginia counties highly vulnerable to rapid HIV dissemination through injection drug use: a cautionary tale
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DOI：
10.1016/j.annepidem.2019.02.012
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发表时间：
2019-06-01
影响因子：
5.6
通讯作者：
Hoots, Brooke E.
中科院分区：
文献类型：
--
作者：
Bradley, Heather;Hogan, Vicki;Hoots, Brooke E.
目的：调查西弗吉尼亚州15个县男男性行为者中HIV聚集性感染向注射毒品者传播HIV的可能性。这些国家以前被确定为极易通过与高水平阿片类药物滥用相关的注射吸毒（IDU）传播艾滋病毒。方法：对2017年确诊的HIV感染者进行访谈，询问其过去一年的风险行为，并询问其性行为、IDU和社会接触情况。我们对接触者进行了艾滋病毒检测，并评估了危险行为。为了确定2017年确诊患者向注射吸毒者传播艾滋病毒的可能性，我们评估了艾滋病毒感染者和接触者的病毒抑制状况、艾滋病毒感染状况以及IDU危险行为。结果：本组共访谈78人，其中2017年确诊39人，接触者39人。总体而言，78人中有13人（17%）在过去一年中注射过毒品。在2017年确诊并可检测到病毒的19人中，9人（47%）有1次以上或等于1次性接触或IDU接触者，其艾滋病毒状况为阴性或未知。在过去一年中，有2/9的人注射过毒品和共用器械，1/9的人有1个以上或等于1个的伴侣这样做。结论：我们确定了2017年确诊患者及其接触者的IDU风险行为。西弗吉尼亚州的艾滋病毒预防项目应继续优先考虑减少注射过量的危害。(C) 2019由爱思唯尔公司出版。
Purpose: To investigate HIV transmission potential from a cluster of HIV infections among men who have sex with men to persons who inject drugs in 15 West Virginia counties. These counties were previously identified as highly vulnerable to rapid HIV dissemination through injection drug use (IDU) associated with high levels of opioid misuse.Methods: We interviewed persons with 2017 HIV diagnoses about past-year risk behaviors and elicited sexual, IDU, and social contacts. We tested contacts for HIV and assessed risk behaviors. To determine HIV transmission potential from persons with 2017 diagnoses to persons who inject drugs, we assessed viral suppression status, HIV status of contacts, and IDU risk behaviors of persons living with HIV and contacts.Results: We interviewed 78 persons: 39 with 2017 diagnoses and 39 contacts. Overall, 13/78 (17%) injected drugs in the past year. Of 19 persons with 2017 diagnoses and detectable virus, 9 (47%) had more than or equal to 1 sexual or IDU contacts of negative or unknown HIV status. During the past year, 2/9 had injected drugs and shared equipment, and 1/9 had more than or equal to 1 partner who did so.Conclusions: We identified IDU risk behavior among persons with 2017 diagnoses and their contacts. West Virginia HIV prevention programs should continue to give high priority to IDU harm reduction. (C) 2019 Published by Elsevier Inc.