Repetitive transcranial magnetic stimulation and drug addiction

Repetitive transcranial magnetic stimulation and drug addiction
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DOI:
10.3109/09540261.2011.618827
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发表时间:
2011-01-01
影响因子:
2.8
通讯作者:
Daskalakis, Zafiris J.
Daskalakis, Zafiris J.
中科院分区:
医学4区
文献类型:
--
作者:
Barr, Mera S.;Farzan, Faranak;Daskalakis, Zafiris J.

文献摘要

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重复经颅磁刺激(rTMS)是一种非侵入性脑刺激技术,目前正在测试其治疗成瘾的能力。这篇综述讨论了目前的研究方法和研究结果,测量rTMS治疗烟草,酒精和非法药物成瘾的治疗用途。该领域的研究有限,因此保留了所有评价rTMS在烟草、酒精或非法药物成瘾中的治疗用途的研究,包括通过NCBI PubMed(http://www.example.com)和手动检索的病例研究。www.ncbi.nlm.nih.gov共有8项研究确定了rTMS治疗烟草,酒精和可卡因成瘾的能力。这篇综述的结果表明,rTMS是有效的,在高频率应用于背外侧前额叶皮层(DLPFC)时,降低吸烟,酒精和可卡因的渴望水平。此外,这些研究表明,在DLPFC上重复进行高频rTMS可能是降低吸烟和饮酒水平的最有效方法。虽然在这方面的工作是有限的,这次审查表明,rTMS是一个很有前途的方式治疗药物成瘾。
Repetitive transcranial magnetic stimulation (rTMS) is a non-invasive brain stimulation technique that is now being tested for its ability to treat addiction. This review discusses current research approaches and results of studies which measured the therapeutic use of rTMS to treat tobacco, alcohol and illicit drug addiction. The research in this area is limited and therefore all studies evaluating the therapeutic use of rTMS in tobacco, alcohol or illicit drug addiction were retained including case studies through NCBI PubMed (http://www.ncbi.nlm.nih.gov) and manual searches. A total of eight studies were identified that examined the ability of rTMS to treat tobacco, alcohol and cocaine addiction. The results of this review indicate that rTMS is effective in reducing the level of cravings for smoking, alcohol, and cocaine when applied at high frequencies to the dorsolateral prefrontal cortex (DLPFC). Furthermore, these studies suggest that repeated sessions of high frequency rTMS over the DLPFC may be most effective in reducing the level of smoking and alcohol consumption. Although work in this area is limited, this review indicates that rTMS is a promising modality for treating drug addiction.