Combination antimicrobial prophylaxis for hysterectomy: harm without the benefit?
Combination antimicrobial prophylaxis for hysterectomy: harm without the benefit?
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子宫切除术的联合抗菌药物预防：有弊无益？
DOI：
10.1016/j.ajog.2018.01.032
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发表时间：
2018
影响因子：
9.8
通讯作者：
Gupta,Kalpana
中科院分区：
文献类型：
--
作者：
Branch-Elliman,Westyn;Ripollone,John;O'Brien,William;Itani,Kamal;Strymish,Judith;Gupta,Kalpana
多项研究结果表明，预防性使用联合抗菌疗法可减少剖宫产和其他外科手术后手术部位感染 (SSI)。然而，最近的一项研究报告称，联合治疗方案与非妇科手术后术后急性肾损伤 (AKI) 的增加有关。 2017 年发表的一项荟萃分析指出，缺乏关于妇科手术中预防方案不良反应的高质量数据。
Results from several studies suggest that prophylactic use of combination antimicrobial regimens reduce postoperative surgical site infections (SSIs) after cesarean delivery and other surgical procedures. A recent study, however, reported that combination regimens were associated with increases in postoperative acute kidney injury (AKI) after nongynecologic surgical procedures. In a meta-analysis published in 2017, the lack of high-quality data on the adverse effects of prophylaxis regimens in gynecologic procedures was noted.