Case studies emphasising the difficulties in the diagnosis and management of alveolar echinococcosis in rural China.
Case studies emphasising the difficulties in the diagnosis and management of alveolar echinococcosis in rural China.
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案例研究强调中国农村肺泡包虫病诊断和治疗的困难
DOI：
10.1186/1756-3305-4-196
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发表时间：
2011-10-09
影响因子：
3.2
通讯作者：
Yang YR
中科院分区：
文献类型：
--
作者：
McManus DP;Li Z;Yang S;Gray DJ;Yang YR
背景人类肺泡包虫病（AE）是由意外摄入狐狸绦虫多房棘球绦虫卵引起的。由于卫生水平差、人与狗密切接触以及缺乏正确、快速诊断疾病的适当设施，AE 在中国西部农村频繁发生。研究结果我们描述了一名患有肝脏 AE 和脑部 AE 转移的患者。她被误诊为疑似未分化的肝癌和脑转移癌，并患有肺部细菌感染，但随后在后续的包虫病现场调查中被正确诊断。脑 AE 的诊断通过神经外科手术中取出的组织活检的病理检查得到证实。我们还简要描述了偶然发现的其他有症状和无症状 AE 病例，这可能是由于中国农村社区用于 AE 诊断和管理的设施不足，因为转移性 AE 的快速、准确诊断需要适当诊断程序的高水平专业知识。结论本报告强调了中国农村地区 AE 诊断、治疗、预防和控制升级的必要性。
BackgroundHuman alveolar echinococcosis (AE) is caused by the accidental ingestion of the eggs of the fox tapewormEchinococcus multilocularis. AE occurs frequently in rural western China due to the poor levels of hygiene, the close contact of people with dogs, and the lack of appropriate facilities for the correct and rapid diagnosis of the disease.FindingsWe describe a case of a patient with hepatic AE, and AE metastases of the brain. She was mistakenly diagnosed with suspected undifferentiated metastatic cancer of the liver and brain, and with a pulmonary bacterial infection, but was subsequently correctly diagnosed during a follow-up field survey for echinococcosis. The diagnosis of brain AE was confirmed by pathological examination of tissue biopsies removed during neurosurgery. We also briefly describe other symptomatic and asymptomatic AE cases, identified by chance, likely due to the inadequate facilities available in rural communities in China for AE diagnosis and management, since the rapid and accurate diagnosis of metastatic AE requires a high level of expertise in the appropriate diagnostic procedures.ConclusionsThis report highlights the necessity for an upgrade in the diagnosis, treatment, prevention and control of AE in rural China.
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影响因子：
11.8
作者：
Tiaoying L;Jiamin Q;Wen Y;Craig PS;Xingwang C;Ning X;Ito A;Giraudoux P;Wulamu M;Wen Y;Schantz PM
通讯作者：
Schantz PM
影响因子：
3.8
作者：
Brunetti E;Garcia HH;Junghanss T;International CE Workshop in Lima, Peru, 2009
通讯作者：
International CE Workshop in Lima, Peru, 2009
影响因子：
1.9
作者：
Kern, P;Wen, H;Bresson-Hadni, S
通讯作者：
Bresson-Hadni, S
影响因子：
3.2
作者：
Yang, Yu Rong;Gray, Darren J.;McManus, Donald P.
通讯作者：
McManus, Donald P.
影响因子：
3.3
作者：
Yang, Y. R.;Williams, G. M.;McManus, D. P.
通讯作者：
McManus, D. P.