Incidence of chronic wounds in Singapore, a multiethnic Asian country, between 2000 and 2017: a retrospective cohort study using a nationwide claims database.

Incidence of chronic wounds in Singapore, a multiethnic Asian country, between 2000 and 2017: a retrospective cohort study using a nationwide claims database.
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DOI:
10.1136/bmjopen-2020-039411
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发表时间:
2020-09-25
期刊:
影响因子:
2.9
通讯作者:
Tan KB
Tan KB
中科院分区:
医学3区
文献类型:
--
作者:
Goh OQ;Ganesan G;Graves N;Ng YZ;Harding K;Tan KB

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慢性创伤很常见,费用昂贵,损害生活质量,但流行病学数据很少。我们的目的是估计多种族亚洲人群的发病趋势。回顾性队列研究。新加坡全国索赔数据库。新加坡人和永久居民。根据2000年至2017年期间所有入院的国际疾病分类第九版澳大利亚修订版(ICD-9-AM)和ICD-10-AM代码识别患者,并根据病因分类:静脉,动脉,糖尿病和血压。从Charlson合并症指数评分的国家数据库中提取合并症。在2000年至2017年期间,在86631名患者中确定了124023起与伤口有关的索赔。所有伤口的创伤特异性发生率(ASR)和年龄调整后的发生率在18年内增加,年龄≥80岁的患者增加最多。2017年,患者的中位年龄为74岁(IQR 63-84)。一半是男性(51%)。70%是华人,15%是马来人,9%是印度人。2017年,静脉伤口的粗发病率(CIR)为15/10万人(95% CI 14至16),动脉伤口为56/10万人(95% CI 53至58),糖尿病伤口为168/10万人(95% CI 164至173),压力伤口为183/10万人(95% CI 179至188)。任何慢性伤口的CIR为296(95% CI 291 - 301)。≥80岁患者的ASR最高:92(95% CI 74 - 112)静脉,478(95% CI 436 - 522)动脉,1791(95% CI 1710 - 1876),血压为3647(95% CI 3530 - 3766),任何伤口为4277(95% CI 4151 - 4407)。与中国人相比,印度人静脉和动脉伤口的ASR是中国人的三倍,糖尿病伤口的ASR是中国人的两倍。马来人的动脉和糖尿病伤口的ASR是前者的两倍。慢性伤口在老年人中很常见,在该亚洲队列中存在显著的种族差异。随着人口老龄化,预计发病率将上升,解决健康差异并评估利用率和成本以告知临床实践和卫生政策至关重要。
Chronic wounds are common, costly and impair quality of life, yet epidemiological data are scarce. We aimed to estimate the incidence trend of a multiethnic Asian population. Retrospective cohort study. Singapore’s nationwide claims database. Singaporeans and permanent residents. Patients were identified by International Classification of Disease, Ninth Revision, Australian Modification (ICD-9-AM) and ICD-10-AM codes from all admissions between 2000 and 2017, and categorised according to aetiology: venous, arterial, diabetic and pressure. Comorbidities were extracted from a national database of Charlson Comorbidity Index scores. Between 2000 and 2017, 124 023 wound-related claims among 86 631 patients were identified. Age-specific rate (ASR) and age-adjusted incidence rates of all wounds increased over 18 years, with greatest increases among those aged ≥80. In 2017, the median age of patients was 74 (IQR 63–84). Half were male (51%). 70% were ethnic Chinese, 15% Malay and 9% Indian. In 2017, the crude incidence rate (CIR) was 15 per 100 000 persons (95% CI 14 to 16) for venous wounds, 56 (95% CI 53 to 58) for arterial, 168 (95% CI 164 to 173) for diabetic and 183 (95% CI 179 to 188) for pressure wounds. The CIR of any chronic wound was 296 (95% CI 291 to 301). ASRs were greatest in patients aged ≥80: 92 (95% CI 74 to 112) for venous, 478 (95% CI 436 to 522) for arterial, 1791 (95% CI 1710 to 1876) for diabetic, 3647 (95% CI 3530 to 3766) for pressure and 4277 (95% CI 4151 to 4407) for any wound. Compared with the Chinese, Indians had thrice the ASRs of venous and arterial wounds and double the ASR of diabetic wounds. Malays had double the ASRs of arterial and diabetic wounds. Chronic wounds are common in the elderly with significant ethnic disparities in this Asian cohort. With the incidence expected to rise with ageing populations, it is crucial to address health disparities and evaluate utilisation and cost to inform clinical practice and health policy.
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