Spatial Distribution of Pancreatic Stones in Chronic Pancreatitis
Spatial Distribution of Pancreatic Stones in Chronic Pancreatitis
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慢性胰腺炎胰腺结石的空间分布
DOI：
10.1097/mpa.0000000000001097
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发表时间：
2018-08
期刊：
影响因子：
2.9
通讯作者：
HuLiang-Hao
中科院分区：
文献类型：
--
作者：
Zeng Xiang-Peng;Zhu XY;Li Bai-Rong;Pan CS;Hao Lu;Pan Jun;Wang Dan;Bi Ya-Wei;Ji Jun-Tao;Liao Zhuan;Xin Lei;Du Ting-ting;Lin Jin-Huan;Zhang Di;Ye Bo;Zou Wen-Bin;Chen Hui;Xie Ting;Zheng Zhao-Hong;Li Zhao-Shen;HuLiang-Hao
目的本研究的目的是建立一个描述慢性胰腺炎（CP）胰腺结石空间分布的标准。方法2012年6月至12月共纳入247例CP胰结石患者。从胰腺结石的三维计算机断层图像的冠状投影中获得二维图像。通过石头重建与识别规划系统计算所有石头的数量(n)和所有石头的质心与每一个石头的质心之间的距离的几何标准差（&sgr;），表示空间分布的不均匀性。结果n和&sgr的平均值；分别为13.6和22.5；N > 13.6和&sgr；> 22.5分别被确定为“多石”和“非均匀”。与酒精性CP相比，特发性CP更不容易发生多发结石（比值比[OR]， 0.310），更容易发生不均匀性结石（比值比[OR]， 3.247）。CP病程中胰腺假性囊肿（OR, 2.211）是多发结石的危险因素，而一/二/三度亲属中糖尿病（OR, 0.382）是多发结石的保护因素。诊断胰腺结石的年龄（OR, 1.022）是不均匀性的危险因素。结论与特发性CP相比，酒精性CP患者胰脏结石更多，分布更均匀。
Objectives The aim of this study was to establish a standard to describe the spatial distribution of pancreatic stones in chronic pancreatitis (CP). Methods Two hundred forty-seven CP patients with pancreatic stones from June to December 2012 were enrolled. Two-dimensional images from coronal projection of 3-dimensional computed tomography images of pancreatic stones were gained. The number (n) of all stones and the geometric standard deviation (&sgr;) of distances between the centroid of all stones and the centroids of every stone that represented the spatial distribution nonuniformity were calculated by Stone Reconstruction and Identification Programming System. Results The mean value of n and &sgr; were 13.6 and 22.5; n > 13.6 and &sgr; > 22.5 were determined as “multistones” and “nonuniform,” respectively. Compared with alcoholic CP, idiopathic CP was less prone to multistones (odds ratio [OR], 0.310) and more prone to nonuniform (OR, 3.247). Pancreatic pseudocyst (OR, 2.211) in CP course was a risk factor of multistones, whereas diabetes mellitus in first-/second-/third-degree relatives (OR, 0.382) was a protective factor. Age at diagnosis of pancreatic stones (OR, 1.022) was a risk factor of nonuniformity. Conclusions Compared with idiopathic CP, alcoholic CP patients were prone to more pancreatic stones that distribute more uniformly.
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影响因子：
7.7
作者：
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影响因子：
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DOI：
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发表时间：
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影响因子：
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