Immune checkpoint inhibitors in kidney transplantation.

Immune checkpoint inhibitors in kidney transplantation.
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肾移植中的免疫检查点抑制剂。

DOI:
10.1097/mot.0000000000001036
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发表时间:
2023
影响因子:
2.2
通讯作者:
Riella,LeonardoV
Riella,LeonardoV
中科院分区:
医学4区
文献类型:
--
作者:
Alzahrani,Nora;AlJurdi,Ayman;Riella,LeonardoV

文献摘要

相似文献

虽然ICI治疗可能与改善患者和恶性肿瘤预后相关,但同种异体移植排斥和丧失的风险很高。需要前瞻性研究来证实ICI治疗SOTRs的益处,并评估最佳的免疫抑制方案修改(如果有的话),以改善移植受者的患者、恶性肿瘤和同种异体移植物预后。
Although ICI treatment may be associated with improved patient and malignancy outcomes, the risk of allograft rejection and loss are high. Prospective studies are needed to confirm the benefits of ICI therapy in SOTRs and to evaluate the optimal immunosuppression regimen modifications, if any, to improve patient, malignancy and allograft outcomes in transplant recipients.