Age-associated alterations in catecholaminergic concentrations, neuronal activity, and alpha 1 receptor densities in female rats.
Age-associated alterations in catecholaminergic concentrations, neuronal activity, and alpha 1 receptor densities in female rats.
复制标题
雌性大鼠儿茶酚胺能浓度、神经元活动和 α1 受体密度与年龄相关的变化。
DOI:
10.1016/0197-4580(89)90043-2
复制
发表时间:
1989
影响因子:
4.2
通讯作者:
Wise,PM
中科院分区:
文献类型:
--
作者:
Weiland,NG;Cohen,IR;Wise,PM
The density of α1-adrenergic receptors and catecholamine concentrations and neuronal activity were assessed in selected estrogen-responsive regions of the hypothalamus and pineal glands. The results of this study demonstrate that the densities of α1-adrenergic receptors and norepinephrine and epinephrine concentrations and activity rate constants are altered in aged rats. The direction and extent of the change depend on the specific brain region and reproductive state of the animals. No widespread decline with increased age was observed in any of the parameters measured.