Diphenylhydantoin inhibition of sodium conductance in squid giant axon.

Diphenylhydantoin inhibition of sodium conductance in squid giant axon.
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二苯乙内酰脲抑制鱿鱼巨轴突中的钠电导。

DOI:
10.1073/pnas.69.7.1758
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发表时间:
1972
影响因子:
11.1
通讯作者:
I. Stillman
I. Stillman
中科院分区:
综合性期刊1区
文献类型:
--
作者:
R. Lipicky;D. Gilbert;I. Stillman

文献摘要

被引文献

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Diphenylhydantoin, in concentration of 5-50 muM, decreases the early, transient (sodium) currents of voltage-clamped squid giant axons. These effects are dose-dependent and largely reversible. It appears that diphenylhydantoin reduces the number of open, early, transient (sodium) channels.