Oral complications at 6months after radiation therapy for head and neck cancer
Oral complications at 6months after radiation therapy for head and neck cancer
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DOI：
10.1111/odi.12710
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发表时间：
2017-11-01
期刊：
影响因子：
3.8
通讯作者：
Brennan, M. T.
中科院分区：
文献类型：
--
作者：
Lalla, R. V.;Treister, N.;Brennan, M. T.
目的探讨头颈部癌（HNC）现代放疗（RT）后6个月口腔并发症的发生情况。方法前瞻性多中心队列研究，对接受调强放疗或更高级放疗的HNC患者进行刺激全唾液流、最大张口度、口腔粘膜炎、口腔疼痛、口腔健康相关生活质量（OH-QOL）、口腔黏膜损伤、口腔对372例放疗前和216例放疗后6个月的受试者进行了口腔卫生和口腔卫生习惯的测定。结果放疗后6个月的受试者的平均刺激唾液流量从1.09 ml/min下降到0.47 ml/min（P
ObjectiveTo examine oral complications 6months after modern radiation therapy (RT) for head and neck cancer (HNC).MethodsProspective multicenter cohort study of patients with HNC receiving intensity-modulated radiation therapy or more advanced RT. Stimulated whole salivary flow, maximal mouth opening, oral mucositis, oral pain, oral health-related quality of life (OH-QOL), and oral hygiene practices were measured in 372 subjects pre-RT and 216 subjects at 6months from the start of RT.ResultsMean stimulated whole salivary flow declined from 1.09 to 0.47ml/min at 6months (p