Does magnetoencephalography add to scalp video-EEG as a diagnostic tool in epilepsy surgery?
Does magnetoencephalography add to scalp video-EEG as a diagnostic tool in epilepsy surgery?
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DOI：
10.1212/01.wnl.0000115122.81621.fe
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发表时间：
2004-03-23
期刊：
影响因子：
9.9
通讯作者：
Papanicolaou, AC
中科院分区：
文献类型：
--
作者：
Pataraia, E;Simos, PG;Papanicolaou, AC
目的：作者评价了发作间期脑磁图（MEG）与长时间发作和发作间期头皮视频脑电图（V-EEG）的灵敏度和选择性，以确定可从术前MEG测试中获益的患者组。方法：作者评价了113例接受手术治疗的难治性癫痫患者。癫痫发作间期和发作期V-EEG和MEG预测的致痫区域被定义为与切除区域完全重叠，部分重叠或不重叠。结果：发作间期30分钟MEG检查检测临床显著癫痫样活动的敏感性为79.2%。使用MEG，我们能够定位切除区域的患者比例（72.3%）比非侵入性V-EEG（40%）。在非定位V-EEG研究的患者中，58.8%的患者和72.8%的V-EEG仅部分识别切除区的患者中，MEG有助于切除区的定位。总体而言，MEG和V-EEG结果在32.3%的病例中等同，并且在40%的患者中使用MEG获得了额外的定位信息。结论：对于V-EEG结果部分或非定位的患者，MEG是最有用的术前计划。
Objective: The authors evaluated the sensitivity and selectivity of interictal magnetoencephalography (MEG) versus prolonged ictal and interictal scalp video-electroencephalography (V-EEG) in order to identify patient groups that would benefit from preoperative MEG testing. Methods: The authors evaluated 113 consecutive patients with medically refractory epilepsy who underwent surgery. The epileptogenic region predicted by interictal and ictal V-EEG and MEG was defined in relation to the resected area as perfectly overlapping with the resected area, partially overlapping, or nonoverlapping. Results: The sensitivity of a 30-minute interictal MEG study for detecting clinically significant epileptiform activity was 79.2%. Using MEG, we were able to localize the resected region in a greater proportion of patients (72.3%) than with noninvasive V-EEG (40%). MEG contributed to the localization of the resected region in 58.8% of the patients with a nonlocalizing V-EEG study and 72.8% of the patients for whom V-EEG only partially identified the resected zone. Overall, MEG and V-EEG results were equivalent in 32.3% of the cases, and additional localization information was obtained using MEG in 40% of the patients. Conclusion: MEG is most useful for presurgical planning in patients who have either partially or nonlocalizing V-EEG results.